CD4+ Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II‐Induced Hypertension

CD4+ Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II‐Induced Hypertension

Background Immune cells are key regulators of the vascular inflammatory response characteristic of hypertension. In hypertensive rodents, regulatory T lymphocytes (Treg, CD4+CD25+) prevented vascular injury, cardiac damage, and endothelial dysfunction of mesenteric arteries. Whether Treg modulate th...

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Bibliographic Details
Main Authors: M. Florencia Iulita, Sonia Duchemin, Diane Vallerand, Tlili Barhoumi, Fernando Alvarez, Roman Istomine, Cyril Laurent, Jessica Youwakim, Pierre Paradis, Nathalie Arbour, Ciriaco A. Piccirillo, Ernesto L. Schiffrin, Hélène Girouard
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
angiotensin
cerebral blood flow
inflammation
interleukin‐10
lymphocyte
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009372

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