Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project
Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥20 years whom the BioBank Japan Pr...
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| Format: | Article |
| Language: | English |
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Japan Epidemiological Association
2017-03-01
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| Series: | Journal of Epidemiology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0917504016301071 |
| _version_ | 1818337276856369152 |
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| author | Koshi Nakamura |
| author_facet | Koshi Nakamura |
| author_sort | Koshi Nakamura |
| collection | DOAJ |
| description | Background: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively.
Methods: Of all Japanese male and female lung cancer patients aged ≥20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality.
Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4%, 55.8%, 10.8%, 22.0% and 11.0% for males and 0.3%, 62.4%, 9.9%, 17.1% and 10.2% for females, respectively. The proportions of histological types in males and females were 56.3% and 82.4% for adenocarcinoma, 26.9% and 8.2% for squamous cell carcinoma, 4.5% and 1.5% for large cell carcinoma, 7.7% and 4.1% for small cell carcinoma and 4.6% and 3.8% for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age.
Conclusions: This study showed the association of several lifestyle and clinical characteristics with all-cause mortality in lung cancer patients. |
| first_indexed | 2024-12-13T14:52:39Z |
| format | Article |
| id | doaj.art-749209579c594508b28fb82414950642 |
| institution | Directory Open Access Journal |
| issn | 0917-5040 1349-9092 |
| language | English |
| last_indexed | 2024-12-13T14:52:39Z |
| publishDate | 2017-03-01 |
| publisher | Japan Epidemiological Association |
| record_format | Article |
| series | Journal of Epidemiology |
| spelling | doaj.art-749209579c594508b28fb824149506422022-12-21T23:41:18ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922017-03-01273, SupplementS49S5710.1016/j.je.2016.12.010Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan ProjectKoshi NakamuraBackground: In Japanese males and females, lung cancer is currently the second and fourth most common type of cancer, and the first and second leading cause of cancer-related deaths, respectively. Methods: Of all Japanese male and female lung cancer patients aged ≥20 years whom the BioBank Japan Project originally enrolled between 2003 and 2008, 764 males and 415 females were registered within 90 days after their diagnosis. We described the lifestyle and clinical characteristics of these patients at study entry. Furthermore, we examined the effect of these characteristics on all-cause mortality. Results: In the lung cancer patients registered within 90 days, the frequencies of occult or stage 0, stage I, II, III and IV were 0.4%, 55.8%, 10.8%, 22.0% and 11.0% for males and 0.3%, 62.4%, 9.9%, 17.1% and 10.2% for females, respectively. The proportions of histological types in males and females were 56.3% and 82.4% for adenocarcinoma, 26.9% and 8.2% for squamous cell carcinoma, 4.5% and 1.5% for large cell carcinoma, 7.7% and 4.1% for small cell carcinoma and 4.6% and 3.8% for others, respectively. Among 1120 participants who registered within 90 days, 572 participants died during 5811 person-years of follow-up. Low body mass index, ever smoker, more advanced stage, squamous cell or small cell carcinoma and high serum carcinoembryonic antigen level at study entry were crudely associated with an increased risk of all-cause mortality after adjustment for age. Conclusions: This study showed the association of several lifestyle and clinical characteristics with all-cause mortality in lung cancer patients.http://www.sciencedirect.com/science/article/pii/S0917504016301071Lung cancerSmokingStageHistological typeMortality |
| spellingShingle | Koshi Nakamura Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project Journal of Epidemiology Lung cancer Smoking Stage Histological type Mortality |
| title | Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project |
| title_full | Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project |
| title_fullStr | Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project |
| title_full_unstemmed | Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project |
| title_short | Characteristics and prognosis of Japanese male and female lung cancer patients: The BioBank Japan Project |
| title_sort | characteristics and prognosis of japanese male and female lung cancer patients the biobank japan project |
| topic | Lung cancer Smoking Stage Histological type Mortality |
| url | http://www.sciencedirect.com/science/article/pii/S0917504016301071 |
| work_keys_str_mv | AT koshinakamura characteristicsandprognosisofjapanesemaleandfemalelungcancerpatientsthebiobankjapanproject |