Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review
Neurofibromatosis type I (NF1) is an autosomal dominant disease, with an incidence of 1/2,500-3,000 births and a prevalence of approximately 1/4,000-5,000 individuals. Genetic mutations in the NF1 gene cause it, affecting neural and skin tissues. Glomus tumor is a benign neoplasm originating from th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Dermatologia (SBD)
2020-12-01
|
| Series: | Surgical & Cosmetic Dermatology |
| Subjects: | |
| Online Access: | http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v12/12_n4_868_en.pdf |
| _version_ | 1811160224266977280 |
|---|---|
| author | Marcia Ferraz Nogueira Jayme de Oliveira Gabriela Machado Dias Junqueira Ana Julia Marçal Pereira Dias |
| author_facet | Marcia Ferraz Nogueira Jayme de Oliveira Gabriela Machado Dias Junqueira Ana Julia Marçal Pereira Dias |
| author_sort | Marcia Ferraz Nogueira |
| collection | DOAJ |
| description | Neurofibromatosis type I (NF1) is an autosomal dominant disease, with an incidence of 1/2,500-3,000 births and a prevalence of approximately 1/4,000-5,000 individuals. Genetic mutations in the NF1 gene cause it, affecting neural and skin tissues. Glomus tumor is a benign neoplasm originating from the glomus, a neuromyoatrial structure of the skin present at the fingertips and involved in thermoregulation. The literature historically considered these tumors isolated and sporadic, but some studies have proved a relationship with neurofibromatosis type I. Thus, patients with neurofibromatosis type 1 should be investigated. The case report provides additional support for the notion that NF1 has a risk associated with multiple glomus tumors. |
| first_indexed | 2024-04-10T05:55:09Z |
| format | Article |
| id | doaj.art-7492892f51644a5baa61fdb2a45e7116 |
| institution | Directory Open Access Journal |
| issn | 1984-8773 |
| language | English |
| last_indexed | 2024-04-10T05:55:09Z |
| publishDate | 2020-12-01 |
| publisher | Sociedade Brasileira de Dermatologia (SBD) |
| record_format | Article |
| series | Surgical & Cosmetic Dermatology |
| spelling | doaj.art-7492892f51644a5baa61fdb2a45e71162023-03-03T17:34:50ZengSociedade Brasileira de Dermatologia (SBD)Surgical & Cosmetic Dermatology1984-87732020-12-0112S222823110.5935/scd1984-8773.20201242543Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature reviewMarcia Ferraz Nogueira0Jayme de Oliveira1Gabriela Machado Dias Junqueira2Ana Julia Marçal Pereira Dias3Department of Dermatology, Faculty of Medicine, Universidade de Santo Amaro, São Paulo (SP), BrazilDepartment of Dermatology, Faculty of Medicine, Universidade de Santo Amaro, São Paulo (SP), BrazilDepartment of Dermatology, Faculty of Medicine, Universidade de Santo Amaro, São Paulo (SP), BrazilDepartment of Dermatology, Faculty of Medicine, Universidade de Santo Amaro, São Paulo (SP), BrazilNeurofibromatosis type I (NF1) is an autosomal dominant disease, with an incidence of 1/2,500-3,000 births and a prevalence of approximately 1/4,000-5,000 individuals. Genetic mutations in the NF1 gene cause it, affecting neural and skin tissues. Glomus tumor is a benign neoplasm originating from the glomus, a neuromyoatrial structure of the skin present at the fingertips and involved in thermoregulation. The literature historically considered these tumors isolated and sporadic, but some studies have proved a relationship with neurofibromatosis type I. Thus, patients with neurofibromatosis type 1 should be investigated. The case report provides additional support for the notion that NF1 has a risk associated with multiple glomus tumors.http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v12/12_n4_868_en.pdfglomus tumorassociationcase reportsneoplasmsneurofibromatoses |
| spellingShingle | Marcia Ferraz Nogueira Jayme de Oliveira Gabriela Machado Dias Junqueira Ana Julia Marçal Pereira Dias Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review Surgical & Cosmetic Dermatology glomus tumor association case reports neoplasms neurofibromatoses |
| title | Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review |
| title_full | Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review |
| title_fullStr | Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review |
| title_full_unstemmed | Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review |
| title_short | Multiple glomus tumor in a patient with neurofibromatosis type 1: a case report and literature review |
| title_sort | multiple glomus tumor in a patient with neurofibromatosis type 1 a case report and literature review |
| topic | glomus tumor association case reports neoplasms neurofibromatoses |
| url | http://www.surgicalcosmetic.org.br/Content/imagebank/pdf/v12/12_n4_868_en.pdf |
| work_keys_str_mv | AT marciaferraznogueira multipleglomustumorinapatientwithneurofibromatosistype1acasereportandliteraturereview AT jaymedeoliveira multipleglomustumorinapatientwithneurofibromatosistype1acasereportandliteraturereview AT gabrielamachadodiasjunqueira multipleglomustumorinapatientwithneurofibromatosistype1acasereportandliteraturereview AT anajuliamarcalpereiradias multipleglomustumorinapatientwithneurofibromatosistype1acasereportandliteraturereview |