Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India
Background: India reported first case of 2009 pandemic influenza A (H1N1) virus infection in May, 2009 and Saurashtra region in August, 2009. We describe the characteristics of fatal cases of 2009 influenza A (H1N1) infection reported in Saurashtra region. Methods: From September, 2009 to January, 2...
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| Format: | Article |
| Language: | English |
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Light House Polyclinic Mangalore
2011-01-01
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| Series: | Online Journal of Health & Allied Sciences |
| Subjects: | |
| Online Access: | http://www.ojhas.org/issue36/2010-4-9.htm |
| _version_ | 1818163158553985024 |
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| author | Rajesh K Chudasama, Umed V Patel, Pramod B Verma, Chikitsa D Amin, Hitesh M Shah, Anupam Banerjee, Ravikant R Patel, |
| author_facet | Rajesh K Chudasama, Umed V Patel, Pramod B Verma, Chikitsa D Amin, Hitesh M Shah, Anupam Banerjee, Ravikant R Patel, |
| author_sort | Rajesh K Chudasama, |
| collection | DOAJ |
| description | Background: India reported first case of 2009 pandemic influenza A (H1N1) virus infection in May, 2009 and Saurashtra region in August, 2009. We describe the characteristics of fatal cases of 2009 influenza A (H1N1) infection reported in Saurashtra region. Methods: From September, 2009 to January, 2010, we observed 71 fatal cases that were infected with 2009 influenza A (H1N1) virus and admitted in different hospitals in Rajkot city. Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing was used to confirm infection; the clinico-epidemiological features were observed and documented. Results: Median age of the deceased (71) was 29 years, and 57.7% were females. Median time observed was 5 days from onset of illness to diagnosis of influenza A (H1N1), and 57.7% were referred from general practitioner (OR=0.42, CI=0.24-0.74). Median hospital stay reported was 3 days. All admitted patients received oseltamivir, but only 16.9% received it within 2 days of onset of illness. The most common symptoms were cough (97.2%), fever (93%), sore throat and shortness of breath. Co-morbid conditions were present in almost half of the patients who ultimately died, the most common of which was pregnancy (OR=0.15, CI=0.04-0.52). Radiological pneumonia was reported in 98% patients. Conclusion: Residing in urban area, delayed referral from general practitioner, presence of co-existing condition, especially pregnancy was responsible for mortality among influenza A (H1N1) infected positive. |
| first_indexed | 2024-12-11T16:45:07Z |
| format | Article |
| id | doaj.art-749b2830267f43fda318f02b41b71b00 |
| institution | Directory Open Access Journal |
| issn | 0972-5997 |
| language | English |
| last_indexed | 2024-12-11T16:45:07Z |
| publishDate | 2011-01-01 |
| publisher | Light House Polyclinic Mangalore |
| record_format | Article |
| series | Online Journal of Health & Allied Sciences |
| spelling | doaj.art-749b2830267f43fda318f02b41b71b002022-12-22T00:58:14ZengLight House Polyclinic MangaloreOnline Journal of Health & Allied Sciences0972-59972011-01-0194Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, IndiaRajesh K Chudasama,Umed V Patel,Pramod B Verma,Chikitsa D Amin,Hitesh M Shah,Anupam Banerjee,Ravikant R Patel,Background: India reported first case of 2009 pandemic influenza A (H1N1) virus infection in May, 2009 and Saurashtra region in August, 2009. We describe the characteristics of fatal cases of 2009 influenza A (H1N1) infection reported in Saurashtra region. Methods: From September, 2009 to January, 2010, we observed 71 fatal cases that were infected with 2009 influenza A (H1N1) virus and admitted in different hospitals in Rajkot city. Real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing was used to confirm infection; the clinico-epidemiological features were observed and documented. Results: Median age of the deceased (71) was 29 years, and 57.7% were females. Median time observed was 5 days from onset of illness to diagnosis of influenza A (H1N1), and 57.7% were referred from general practitioner (OR=0.42, CI=0.24-0.74). Median hospital stay reported was 3 days. All admitted patients received oseltamivir, but only 16.9% received it within 2 days of onset of illness. The most common symptoms were cough (97.2%), fever (93%), sore throat and shortness of breath. Co-morbid conditions were present in almost half of the patients who ultimately died, the most common of which was pregnancy (OR=0.15, CI=0.04-0.52). Radiological pneumonia was reported in 98% patients. Conclusion: Residing in urban area, delayed referral from general practitioner, presence of co-existing condition, especially pregnancy was responsible for mortality among influenza A (H1N1) infected positive.http://www.ojhas.org/issue36/2010-4-9.htmInfluenza A (H1N1)EpidemiologyFatal casesRT-PCRPregnancyAntiviral drug |
| spellingShingle | Rajesh K Chudasama, Umed V Patel, Pramod B Verma, Chikitsa D Amin, Hitesh M Shah, Anupam Banerjee, Ravikant R Patel, Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India Online Journal of Health & Allied Sciences Influenza A (H1N1) Epidemiology Fatal cases RT-PCR Pregnancy Antiviral drug |
| title | Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India |
| title_full | Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India |
| title_fullStr | Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India |
| title_full_unstemmed | Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India |
| title_short | Characteristics of Fatal Cases of Pandemic Influenza A (H1N1) from September 2009 to January 2010 in Saurashtra Region, India |
| title_sort | characteristics of fatal cases of pandemic influenza a h1n1 from september 2009 to january 2010 in saurashtra region india |
| topic | Influenza A (H1N1) Epidemiology Fatal cases RT-PCR Pregnancy Antiviral drug |
| url | http://www.ojhas.org/issue36/2010-4-9.htm |
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