Valproic acid counteracts polycyclic aromatic hydrocarbons (PAHs)-induced tumorigenic effects by regulating the polarization of macrophages

Polycyclic aromatic hydrocarbons (PAHs) are common persistent organic pollutants that are carcinogenic, teratogenic and mutagenic, causing a variety of harm to human health. In this study, we investigated the mechanism of how valproic acid (VPA) interferes with the carcinogenesis of PAHs protect nor...

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Bibliographic Details
Main Authors: Yisha Zhang, David Lim, Zuchao Cai, Junxuan Peng, Beidi Jia, Guoliang Chu, Fengmei Zhang, Chao Dong, Zhihui Feng
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322006194