Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved

Inhibition of Orbivirus Replication by Fluvastatin and Identification of the Key Elements of the Mevalonate Pathway Involved

Statin derivatives can inhibit the replication of a range of viruses, including hepatitis C virus (HCV, <i>Hepacivirus</i>), dengue virus (<i>Flavivirus</i>), African swine fever virus (<i>Asfarviridae</i>) and poliovirus (<i>Picornaviridae</i>). We as...

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Bibliographic Details
Main Authors: Fauziah Mohd Jaafar, Baptiste Monsion, Mourad Belhouchet, Peter P. C. Mertens, Houssam Attoui
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
bluetongue virus
BTV
orbivirus
antiviral
fluvastatin
HMG-CoA reductase
Online Access:https://www.mdpi.com/1999-4915/13/8/1437

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