KIF5B plays important roles in dendritic spine plasticity and dendritic localization of PSD95 and FMRP in the mouse cortex in vivo

KIF5B plays important roles in dendritic spine plasticity and dendritic localization of PSD95 and FMRP in the mouse cortex in vivo

Summary: Kinesin 1 (KIF5) is one major type of motor protein in neurons, but its members’ function in the intact brain remains less studied. Using in vivo two-photon imaging, we find that conditional knockout of Kif5b (KIF5B cKO) in CaMKIIα-Cre-expressing neurons shows heightened turnover and lower...

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Bibliographic Details
Main Authors: Albert Hiu Ka Fok, Yuhua Huang, Beth Wing Lam So, Qiyu Zheng, Chun Sing Carlos Tse, Xiaoyang Li, Kenneth Kin-Yip Wong, Jiandong Huang, Kwok-On Lai, Cora Sau Wan Lai
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724002341

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