Detection of DNA damage by alkaline comet assay in mouse colonic mucosa

Detection of DNA damage by alkaline comet assay in mouse colonic mucosa

Summary: We recently characterized the association between DNA damage and immunoresponse in vivo in colonic mucosa of mice infected with a Salmonella Typhimurium strain expressing a genotoxin, known as typhoid toxin. In this protocol, we describe the specific steps for assessing DNA damage by the al...

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Bibliographic Details
Main Authors: Elisa Boutet-Robinet, Maria M. Haykal, Saleha Hashim, Teresa Frisan, Océane C.B. Martin
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Cell isolation
Cell-based Assays
Microscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005785

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