<i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods
<i>Cyclospora cayetanensis</i> infections are prevalent worldwide, and the parasite has become a major public health and food safety concern. Although important efforts have been dedicated to advance toward preventing and reducing incidences of cyclosporiasis, there are still several kno...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/11/9/2171 |
| _version_ | 1797578740859928576 |
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| author | Sonia Almeria Leonor Chacin-Bonilla Jenny G. Maloney Monica Santin |
| author_facet | Sonia Almeria Leonor Chacin-Bonilla Jenny G. Maloney Monica Santin |
| author_sort | Sonia Almeria |
| collection | DOAJ |
| description | <i>Cyclospora cayetanensis</i> infections are prevalent worldwide, and the parasite has become a major public health and food safety concern. Although important efforts have been dedicated to advance toward preventing and reducing incidences of cyclosporiasis, there are still several knowledge gaps that hamper the implementation of effective measures to prevent the contamination of produce and water with <i>Cyclospora</i> oocysts. Some of these data gaps can be attributed to the fact that access to oocysts is a limiting factor in <i>C. cayetanensis</i> research. There are no animal models or in vivo or in vitro culture systems to propagate the oocysts needed to facilitate <i>C. cayetanensis</i> research. Thus, researchers must rely upon limited supplies of oocysts obtained from naturally infected human patients considerably restricting what can be learnt about this parasite. Despite the limited supply of <i>C. cayetanensis</i> oocysts, several important advances have happened in the past 3 years. Great progress has been made in the <i>Cyclospora</i> field in the areas of molecular characterization of strains and species, generation of genomes, and development of novel detection methods. This comprehensive perspective summarizes research published from 2020 to 2023 and evaluates what we have learnt and identifies those aspects in which further research is needed. |
| first_indexed | 2024-03-10T22:27:03Z |
| format | Article |
| id | doaj.art-74b11662c7374f279e7fa9ae7916fd68 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T22:27:03Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-74b11662c7374f279e7fa9ae7916fd682023-11-19T12:01:33ZengMDPI AGMicroorganisms2076-26072023-08-01119217110.3390/microorganisms11092171<i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection MethodsSonia Almeria0Leonor Chacin-Bonilla1Jenny G. Maloney2Monica Santin3Center for Food Safety and Nutrition (CFSAN), Department of Health and Human Services, Food and Drug Administration, Office of Applied Research and Safety Assessment (OARSA), Division of Virulence Assessment, Laurel, MD 20708, USAInstitute of Clinical Research, University of Zulia, Maracaibo 4001-A, VenezuelaEnvironmental Microbial and Food Safety Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USAEnvironmental Microbial and Food Safety Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA<i>Cyclospora cayetanensis</i> infections are prevalent worldwide, and the parasite has become a major public health and food safety concern. Although important efforts have been dedicated to advance toward preventing and reducing incidences of cyclosporiasis, there are still several knowledge gaps that hamper the implementation of effective measures to prevent the contamination of produce and water with <i>Cyclospora</i> oocysts. Some of these data gaps can be attributed to the fact that access to oocysts is a limiting factor in <i>C. cayetanensis</i> research. There are no animal models or in vivo or in vitro culture systems to propagate the oocysts needed to facilitate <i>C. cayetanensis</i> research. Thus, researchers must rely upon limited supplies of oocysts obtained from naturally infected human patients considerably restricting what can be learnt about this parasite. Despite the limited supply of <i>C. cayetanensis</i> oocysts, several important advances have happened in the past 3 years. Great progress has been made in the <i>Cyclospora</i> field in the areas of molecular characterization of strains and species, generation of genomes, and development of novel detection methods. This comprehensive perspective summarizes research published from 2020 to 2023 and evaluates what we have learnt and identifies those aspects in which further research is needed.https://www.mdpi.com/2076-2607/11/9/2171<i>Cyclospora cayetanensis</i>epidemiologyfood safetymethodologyoutbreaksreview |
| spellingShingle | Sonia Almeria Leonor Chacin-Bonilla Jenny G. Maloney Monica Santin <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods Microorganisms <i>Cyclospora cayetanensis</i> epidemiology food safety methodology outbreaks review |
| title | <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods |
| title_full | <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods |
| title_fullStr | <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods |
| title_full_unstemmed | <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods |
| title_short | <i>Cyclospora cayetanensis</i>: A Perspective (2020–2023) with Emphasis on Epidemiology and Detection Methods |
| title_sort | i cyclospora cayetanensis i a perspective 2020 2023 with emphasis on epidemiology and detection methods |
| topic | <i>Cyclospora cayetanensis</i> epidemiology food safety methodology outbreaks review |
| url | https://www.mdpi.com/2076-2607/11/9/2171 |
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