Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion

Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion

Introduction: NBP is a compound isolated from celery seeds, which was approved by the National Medical Products Administration in 2002 for clinical treatment of ischemic stroke. However, in brain ischemia/reperfusion (I/R) injury, the related research on mitochondrial dynamics and its mechanism of a...

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Bibliographic Details
Main Authors: Ting Zhu, Shanshan Dong, Na Qin, Rujuan Liu, Liuliu Shi, Qi Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
ischemic stroke
Dl-3-n-butylphthalide
mitochondrial fusion
AMPK
Mfn1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1357953/full

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