Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study
In young cattle, bovine respiratory disease (BRD) is a major cause of death and <i>Mannheimia haemolytica</i> is a frequent pathogen. Knowledge of fatal BRD in adult cattle is more limited. We assessed the importance of infectious BRD as a cause of death in adult cattle and determined th...
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MDPI AG
2021-08-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/8/2280 |
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| author | Laëtitia Dorso Maud Rouault Claire Barbotin Christophe Chartier Sébastien Assié |
| author_facet | Laëtitia Dorso Maud Rouault Claire Barbotin Christophe Chartier Sébastien Assié |
| author_sort | Laëtitia Dorso |
| collection | DOAJ |
| description | In young cattle, bovine respiratory disease (BRD) is a major cause of death and <i>Mannheimia haemolytica</i> is a frequent pathogen. Knowledge of fatal BRD in adult cattle is more limited. We assessed the importance of infectious BRD as a cause of death in adult cattle and determined the associated pathogens. We analyzed data from 737 adult cattle necropsies at the Pathology Unit for Large Animals at Oniris, Nantes, France over a 6 year period (2013–2019). Each carcass was subjected to a complete necropsy. Lungs showing macroscopic lesions were classified into three categories: infectious primary pulmonary (IPP) lesions, thromboembolic pneumonia (TEP) and others (aspiration pneumonia, verminous pneumonia, and local extension of an extra-pulmonary inflammatory process). Half of the lungs with IPP macroscopic lesions were sampled for histology and submitted for polymerase chain reaction. BRD was the second leading cause of death (15.7%) after digestive diseases (32.2%). A strong predominance of IPP lesions (42.3%) and TEP lesions (39.6%) was also demonstrated. In IPP macroscopic lesions, fibrinous, hemorrhagic and/or hecrotic (FHN) bronchopneumonia accounted for 77.6% of macroscopic lesions. <i>Mannheimia haemolytica</i> was significantly associated with FHN bronchopneumonia macroscopic lesions. This study suggests that <i>Mannheimia haemolytica</i> should be included in the differential diagnosis of BRD in adult cattle. |
| first_indexed | 2024-03-10T09:04:22Z |
| format | Article |
| id | doaj.art-74b5cc6e91bd464393572262ad1430f0 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T09:04:22Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-74b5cc6e91bd464393572262ad1430f02023-11-22T06:29:50ZengMDPI AGAnimals2076-26152021-08-01118228010.3390/ani11082280Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological StudyLaëtitia Dorso0Maud Rouault1Claire Barbotin2Christophe Chartier3Sébastien Assié4INRAE, Oniris, BIOEPAR, 44300 Nantes, FranceINRAE, Oniris, BIOEPAR, 44300 Nantes, FranceINRAE, Oniris, BIOEPAR, 44300 Nantes, FranceINRAE, Oniris, BIOEPAR, 44300 Nantes, FranceINRAE, Oniris, BIOEPAR, 44300 Nantes, FranceIn young cattle, bovine respiratory disease (BRD) is a major cause of death and <i>Mannheimia haemolytica</i> is a frequent pathogen. Knowledge of fatal BRD in adult cattle is more limited. We assessed the importance of infectious BRD as a cause of death in adult cattle and determined the associated pathogens. We analyzed data from 737 adult cattle necropsies at the Pathology Unit for Large Animals at Oniris, Nantes, France over a 6 year period (2013–2019). Each carcass was subjected to a complete necropsy. Lungs showing macroscopic lesions were classified into three categories: infectious primary pulmonary (IPP) lesions, thromboembolic pneumonia (TEP) and others (aspiration pneumonia, verminous pneumonia, and local extension of an extra-pulmonary inflammatory process). Half of the lungs with IPP macroscopic lesions were sampled for histology and submitted for polymerase chain reaction. BRD was the second leading cause of death (15.7%) after digestive diseases (32.2%). A strong predominance of IPP lesions (42.3%) and TEP lesions (39.6%) was also demonstrated. In IPP macroscopic lesions, fibrinous, hemorrhagic and/or hecrotic (FHN) bronchopneumonia accounted for 77.6% of macroscopic lesions. <i>Mannheimia haemolytica</i> was significantly associated with FHN bronchopneumonia macroscopic lesions. This study suggests that <i>Mannheimia haemolytica</i> should be included in the differential diagnosis of BRD in adult cattle.https://www.mdpi.com/2076-2615/11/8/2280adult cattlenecropsybovine respiratory diseasesthromboembolic pneumonia<i>Mannheimia haemolytica</i> |
| spellingShingle | Laëtitia Dorso Maud Rouault Claire Barbotin Christophe Chartier Sébastien Assié Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study Animals adult cattle necropsy bovine respiratory diseases thromboembolic pneumonia <i>Mannheimia haemolytica</i> |
| title | Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study |
| title_full | Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study |
| title_fullStr | Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study |
| title_full_unstemmed | Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study |
| title_short | Infectious Bovine Respiratory Diseases in Adult Cattle: An Extensive Necropsic and Etiological Study |
| title_sort | infectious bovine respiratory diseases in adult cattle an extensive necropsic and etiological study |
| topic | adult cattle necropsy bovine respiratory diseases thromboembolic pneumonia <i>Mannheimia haemolytica</i> |
| url | https://www.mdpi.com/2076-2615/11/8/2280 |
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