Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report

Patients with kidney transplants are at greater risk of contracting COVID-19 because of long-term immunosuppression and may end up with severe disease with adverse outcome. The experiences of COVID-19 management in kidney transplant recipients are limited. This is a case of COVID-19 in a 45-year-old...

Full description

Bibliographic Details
Main Authors: Martin Thomas Kurian, Syed Arman Rabbani, Ajith Cherian Thomas, Nadeem Javed
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2022-01-01
Series:Journal of Nephropathology
Subjects:
Online Access:https://nephropathol.com/PDF/jnp-11-e9.pdf
_version_ 1797828049731846144
author Martin Thomas Kurian
Syed Arman Rabbani
Ajith Cherian Thomas
Nadeem Javed
author_facet Martin Thomas Kurian
Syed Arman Rabbani
Ajith Cherian Thomas
Nadeem Javed
author_sort Martin Thomas Kurian
collection DOAJ
description Patients with kidney transplants are at greater risk of contracting COVID-19 because of long-term immunosuppression and may end up with severe disease with adverse outcome. The experiences of COVID-19 management in kidney transplant recipients are limited. This is a case of COVID-19 in a 45-year-old patient with a second renal transplant on triple immunosuppressive therapy who was successfully treated for COVID-19, septic shock, acute kidney injury and was discharged with a stable graft function. The patient presented with mild COVID-19 symptoms but later went into septic shock followed by acute kidney injury due to a secondary bacterial infection. The patient was successfully managed using antivirals, corticosteroids, reducing the dose of immunosuppressants initially, then discontinuing all the immunosuppressants in view of septic shock and finally reinstating the immunosuppression gradually on clinical improvement. This case report may serve as a reference for treating immunocompromised kidney transplant recipients having COVID-19. However, more data and experiences are needed for optimization of treatment of kidney transplant recipients with COVID-19.
first_indexed 2024-04-09T12:58:13Z
format Article
id doaj.art-74bc0dc3dec7402fbb1e1c9d7d89b419
institution Directory Open Access Journal
issn 2251-8363
2251-8819
language English
last_indexed 2024-04-09T12:58:13Z
publishDate 2022-01-01
publisher Society of Diabetic Nephropathy Prevention
record_format Article
series Journal of Nephropathology
spelling doaj.art-74bc0dc3dec7402fbb1e1c9d7d89b4192023-05-13T11:05:11ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192022-01-01111e9e910.34172/jnp.2022.09jnp-17216Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case reportMartin Thomas Kurian0Syed Arman Rabbani1Ajith Cherian Thomas2Nadeem Javed3Ibrahim Bin Hamad Obaidallah Hospital, Ras al Khaimah, United Arab EmiratesRAK Medical and Health Sciences University, Ras Al-Khaimah, United Arab EmiratesIbrahim Bin Hamad Obaidallah Hospital, Ras al Khaimah, United Arab EmiratesIbrahim Bin Hamad Obaidallah Hospital, Ras al Khaimah, United Arab EmiratesPatients with kidney transplants are at greater risk of contracting COVID-19 because of long-term immunosuppression and may end up with severe disease with adverse outcome. The experiences of COVID-19 management in kidney transplant recipients are limited. This is a case of COVID-19 in a 45-year-old patient with a second renal transplant on triple immunosuppressive therapy who was successfully treated for COVID-19, septic shock, acute kidney injury and was discharged with a stable graft function. The patient presented with mild COVID-19 symptoms but later went into septic shock followed by acute kidney injury due to a secondary bacterial infection. The patient was successfully managed using antivirals, corticosteroids, reducing the dose of immunosuppressants initially, then discontinuing all the immunosuppressants in view of septic shock and finally reinstating the immunosuppression gradually on clinical improvement. This case report may serve as a reference for treating immunocompromised kidney transplant recipients having COVID-19. However, more data and experiences are needed for optimization of treatment of kidney transplant recipients with COVID-19.https://nephropathol.com/PDF/jnp-11-e9.pdfcovid-19kidney transplant recipientsimmunosuppressionantiviralscorticosteroids
spellingShingle Martin Thomas Kurian
Syed Arman Rabbani
Ajith Cherian Thomas
Nadeem Javed
Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
Journal of Nephropathology
covid-19
kidney transplant recipients
immunosuppression
antivirals
corticosteroids
title Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
title_full Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
title_fullStr Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
title_full_unstemmed Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
title_short Coronavirus disease 2019 (COVID-19) in a kidney transplant recipient; case report
title_sort coronavirus disease 2019 covid 19 in a kidney transplant recipient case report
topic covid-19
kidney transplant recipients
immunosuppression
antivirals
corticosteroids
url https://nephropathol.com/PDF/jnp-11-e9.pdf
work_keys_str_mv AT martinthomaskurian coronavirusdisease2019covid19inakidneytransplantrecipientcasereport
AT syedarmanrabbani coronavirusdisease2019covid19inakidneytransplantrecipientcasereport
AT ajithcherianthomas coronavirusdisease2019covid19inakidneytransplantrecipientcasereport
AT nadeemjaved coronavirusdisease2019covid19inakidneytransplantrecipientcasereport