miRNA‐122‐5p in POI ovarian‐derived exosomes promotes granulosa cell apoptosis by regulating BCL9

miRNA‐122‐5p in POI ovarian‐derived exosomes promotes granulosa cell apoptosis by regulating BCL9

Abstract This study is to explore the therapeutic effect and potential mechanisms of exosomal microRNAs (miRNAs) derived from the ovaries with primary ovarian insufficiency (POI). The POI mouse model was established by intraperitoneal injection of cyclophosphamide (CTX) and busulfan. The apoptosis o...

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Bibliographic Details
Main Authors: Xiujuan Zhang, Ruihong Zhang, Jing Hao, Xiaoyan Huang, Ming Liu, Mengxiao Lv, Chan Su, Yu‐Lan Mu
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Cancer Medicine
Subjects:
BCL9
exosome
miR‐122‐5p
ovarian granulosa cell
premature ovarian insufficiency
Online Access:https://doi.org/10.1002/cam4.4615

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