Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia
Abstract Objective S. pneumoniae responsible for a range of respiratory infections from uncomplicated to severe invasive pneumococcal disease. Nasopharyngeal specimens were collected from children attending kindergarten and aged ≤ 6 years from February, 2017 to June, 2017 to assess the nasopharyngea...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-05-01
|
| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13104-019-4283-3 |
| _version_ | 1811225750005612544 |
|---|---|
| author | Gizaw Abaye Hailu Fekadu Kelili Haji Desalegn Alemu Antehun Alemayehu Anjulo Debela T. Yadate |
| author_facet | Gizaw Abaye Hailu Fekadu Kelili Haji Desalegn Alemu Antehun Alemayehu Anjulo Debela T. Yadate |
| author_sort | Gizaw Abaye |
| collection | DOAJ |
| description | Abstract Objective S. pneumoniae responsible for a range of respiratory infections from uncomplicated to severe invasive pneumococcal disease. Nasopharyngeal specimens were collected from children attending kindergarten and aged ≤ 6 years from February, 2017 to June, 2017 to assess the nasopharyngeal carriage and antimicrobial susceptibility pattern of S. pneumoniae. Parents of children interviewed using questionnaire and check list to identify associated factors. An antimicrobial susceptibility test performed using disk diffusion method. Results Overall pneumococcal carriage were 18.4% (88/477). No significant variation in colonization based on sex and age of children. Children living with siblings (1–2) < 6 years in household (adjusted odd ratio = 16.06; 95% confidence interval 6.21–41.55) and > 5 person per household (adjusted odd ratio = 3.27; 95% confidence interval 1.50–7.14) were associated with higher S. pneumoniae carriage. Non- exclusive breast feeding (adjust odd ratio = 6.00; 95% confidence interval 3.33–10.80) and horse cart transportation (adjusted odd ratio = 2.75; 95% confidence interval 1.05–7.22) increases carriage. S. pneumoniae showed 21 (23.9%) resistance to erythromycin, 18 (20.4%) to amoxicillin, 13 (15.0%) to penicillin, and the least 1 (1.1%) to augmentin. |
| first_indexed | 2024-04-12T09:12:41Z |
| format | Article |
| id | doaj.art-74c27486d5c0435f9570e65026a3bbad |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-12T09:12:41Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-74c27486d5c0435f9570e65026a3bbad2022-12-22T03:38:55ZengBMCBMC Research Notes1756-05002019-05-011211610.1186/s13104-019-4283-3Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, EthiopiaGizaw Abaye0Hailu Fekadu1Kelili Haji2Desalegn Alemu3Antehun Alemayehu Anjulo4Debela T. Yadate5Department of Medical Laboratory Science, College of Health Sciences, Arsi UniversityDepartment of Public Health, College of Health Sciences, Arsi UniversityDepartment of Anatomy, College of Health Sciences, Arsi UniversityDepartment of Medical Laboratory Science, College of Health Sciences, Arsi UniversityDepartment of Medical Laboratory, College of Health Sciences and Medicine, Wolaita Sodo UniversityDepartment of Physiology, College of Health Sciences, Arsi UniversityAbstract Objective S. pneumoniae responsible for a range of respiratory infections from uncomplicated to severe invasive pneumococcal disease. Nasopharyngeal specimens were collected from children attending kindergarten and aged ≤ 6 years from February, 2017 to June, 2017 to assess the nasopharyngeal carriage and antimicrobial susceptibility pattern of S. pneumoniae. Parents of children interviewed using questionnaire and check list to identify associated factors. An antimicrobial susceptibility test performed using disk diffusion method. Results Overall pneumococcal carriage were 18.4% (88/477). No significant variation in colonization based on sex and age of children. Children living with siblings (1–2) < 6 years in household (adjusted odd ratio = 16.06; 95% confidence interval 6.21–41.55) and > 5 person per household (adjusted odd ratio = 3.27; 95% confidence interval 1.50–7.14) were associated with higher S. pneumoniae carriage. Non- exclusive breast feeding (adjust odd ratio = 6.00; 95% confidence interval 3.33–10.80) and horse cart transportation (adjusted odd ratio = 2.75; 95% confidence interval 1.05–7.22) increases carriage. S. pneumoniae showed 21 (23.9%) resistance to erythromycin, 18 (20.4%) to amoxicillin, 13 (15.0%) to penicillin, and the least 1 (1.1%) to augmentin.http://link.springer.com/article/10.1186/s13104-019-4283-3Nasopharyngeal carriageS. pneumoniaeAntimicrobial susceptibility patternRisk factors |
| spellingShingle | Gizaw Abaye Hailu Fekadu Kelili Haji Desalegn Alemu Antehun Alemayehu Anjulo Debela T. Yadate Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia BMC Research Notes Nasopharyngeal carriage S. pneumoniae Antimicrobial susceptibility pattern Risk factors |
| title | Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia |
| title_full | Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia |
| title_fullStr | Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia |
| title_full_unstemmed | Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia |
| title_short | Prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten, in district of Arsi Zone, South East, Ethiopia |
| title_sort | prevalence and risk factors of pneumococcal nasopharyngeal carriage in healthy children attending kindergarten in district of arsi zone south east ethiopia |
| topic | Nasopharyngeal carriage S. pneumoniae Antimicrobial susceptibility pattern Risk factors |
| url | http://link.springer.com/article/10.1186/s13104-019-4283-3 |
| work_keys_str_mv | AT gizawabaye prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia AT hailufekadu prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia AT kelilihaji prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia AT desalegnalemu prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia AT antehunalemayehuanjulo prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia AT debelatyadate prevalenceandriskfactorsofpneumococcalnasopharyngealcarriageinhealthychildrenattendingkindergartenindistrictofarsizonesoutheastethiopia |