Preclinical evaluation of pentagamavunone-1 as monotherapy and combination therapy for pancreatic cancer in multiple xenograft models
Abstract We previously reported that pentagamavunone-1 (PGV-1) effectively inhibited cell proliferation in many types of human tumors, including pancreatic cancer, by inducing M phase (prometaphase) arrest, senescence, and apoptosis with few side effects. However, a detailed evaluation of the effect...
| Հիմնական հեղինակներ: | , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Nature Portfolio
2022-12-01
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| Շարք: | Scientific Reports |
| Առցանց հասանելիություն: | https://doi.org/10.1038/s41598-022-26863-y |