In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer’s Disease

In Vitro Astroglial Dysfunction Induced by Neurotoxins: Mimicking Astrocytic Metabolic Alterations of Alzheimer’s Disease

Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers GFAP and S100B, in addition to alterations in some of its metabolic functi...

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Bibliographic Details
Main Authors: Jéssica Taday, Fernanda Telles Fróes, Marina Seady, Carlos Alberto Gonçalves, Marina Concli Leite
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Metabolites
Subjects:
astrocytes
Alzheimer’s disease
streptozotocin
lipopolysaccharide
fluorocitrate
methylglyoxal
Online Access:https://www.mdpi.com/2218-1989/14/3/151

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