Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides
Thermoresponsive Pluronic® F127 (PL) gels in water were investigated through rheological tests in different shear conditions. The gel strength was tuned with the addition of 1% polysaccharide solution. In the presence of xanthan gum (XG), the viscoelastic behavior of PL-based hydrogels was improved...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/9/9/719 |
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| author | Alexandra Lupu Luiza Madalina Gradinaru Daniela Rusu Maria Bercea |
| author_facet | Alexandra Lupu Luiza Madalina Gradinaru Daniela Rusu Maria Bercea |
| author_sort | Alexandra Lupu |
| collection | DOAJ |
| description | Thermoresponsive Pluronic® F127 (PL) gels in water were investigated through rheological tests in different shear conditions. The gel strength was tuned with the addition of 1% polysaccharide solution. In the presence of xanthan gum (XG), the viscoelastic behavior of PL-based hydrogels was improved in aqueous environment, but the rheological behavior was less changed with the addition of XG in PBS solutions, whereas in the presence of 0.1 M NaCl, the viscoelastic parameters decreased. PL micellar networks exhibited a self-healing ability, recovering their initial structure after applying cycles of high strain. The rheological characteristics of the PL hydrogel changed with the addition of 1% polysaccharides (xanthan gum, alginate, κ-carrageenan, gellan, or chitosan). PL/polysaccharide systems form temperature-responsive hydrogels with shear thinning behavior, yield stress, and self-healing ability, being considered a versatile platform for injectable biomaterials or bioinks. Thus, in the presence of xanthan gum in aqueous medium, the gel strength was improved after applying a high strain (the values of elastic modulus increased). The other investigated natural polymers induced specific self-healing behaviors. Good performances were observed with the addition of gellan gum, alginate, and κ-carrageenan, but for high values of strain, the ability to recover the initial structure decreased. A modest self-healing behavior was observed in the presence of chitosan and xanthan gum dissolved in NaCl solution. |
| first_indexed | 2024-03-10T22:44:23Z |
| format | Article |
| id | doaj.art-74ca3d2f9a804f8ba387daf7700da49b |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-10T22:44:23Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-74ca3d2f9a804f8ba387daf7700da49b2023-11-19T10:50:52ZengMDPI AGGels2310-28612023-09-019971910.3390/gels9090719Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various PolysaccharidesAlexandra Lupu0Luiza Madalina Gradinaru1Daniela Rusu2Maria Bercea3“Petru Poni” Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania“Petru Poni” Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania“Petru Poni” Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, Romania“Petru Poni” Institute of Macromolecular Chemistry, 41-A Grigore Ghica Voda Alley, 700487 Iasi, RomaniaThermoresponsive Pluronic® F127 (PL) gels in water were investigated through rheological tests in different shear conditions. The gel strength was tuned with the addition of 1% polysaccharide solution. In the presence of xanthan gum (XG), the viscoelastic behavior of PL-based hydrogels was improved in aqueous environment, but the rheological behavior was less changed with the addition of XG in PBS solutions, whereas in the presence of 0.1 M NaCl, the viscoelastic parameters decreased. PL micellar networks exhibited a self-healing ability, recovering their initial structure after applying cycles of high strain. The rheological characteristics of the PL hydrogel changed with the addition of 1% polysaccharides (xanthan gum, alginate, κ-carrageenan, gellan, or chitosan). PL/polysaccharide systems form temperature-responsive hydrogels with shear thinning behavior, yield stress, and self-healing ability, being considered a versatile platform for injectable biomaterials or bioinks. Thus, in the presence of xanthan gum in aqueous medium, the gel strength was improved after applying a high strain (the values of elastic modulus increased). The other investigated natural polymers induced specific self-healing behaviors. Good performances were observed with the addition of gellan gum, alginate, and κ-carrageenan, but for high values of strain, the ability to recover the initial structure decreased. A modest self-healing behavior was observed in the presence of chitosan and xanthan gum dissolved in NaCl solution.https://www.mdpi.com/2310-2861/9/9/719Pluronic® F127thermoresponsive hydrogelsxanthan gumshear-thinningyield stressself-healing ability |
| spellingShingle | Alexandra Lupu Luiza Madalina Gradinaru Daniela Rusu Maria Bercea Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides Gels Pluronic® F127 thermoresponsive hydrogels xanthan gum shear-thinning yield stress self-healing ability |
| title | Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides |
| title_full | Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides |
| title_fullStr | Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides |
| title_full_unstemmed | Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides |
| title_short | Self-Healing of Pluronic® F127 Hydrogels in the Presence of Various Polysaccharides |
| title_sort | self healing of pluronic r f127 hydrogels in the presence of various polysaccharides |
| topic | Pluronic® F127 thermoresponsive hydrogels xanthan gum shear-thinning yield stress self-healing ability |
| url | https://www.mdpi.com/2310-2861/9/9/719 |
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