An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?

Pharmaceutical analysis guarantees patient safety all over the world. Thus, continuous development of existing analytical techniques is still very important. Pressurized capillary electrochromatography and pressure-assisted capillary electrochromatography are hybrid separation techniques that combin...

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Main Authors: Trzebiatowski Michal Zmuda, Gwarda Radoslaw L., Dzido Tadeusz H.
Format: Article
Language:English
Published: Sciendo 2019-06-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.2478/cipms-2019-0018
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author Trzebiatowski Michal Zmuda
Gwarda Radoslaw L.
Dzido Tadeusz H.
author_facet Trzebiatowski Michal Zmuda
Gwarda Radoslaw L.
Dzido Tadeusz H.
author_sort Trzebiatowski Michal Zmuda
collection DOAJ
description Pharmaceutical analysis guarantees patient safety all over the world. Thus, continuous development of existing analytical techniques is still very important. Pressurized capillary electrochromatography and pressure-assisted capillary electrochromatography are hybrid separation techniques that combine the selectivity of liquid chromatography and the high separation efficiency of capillary electrophoresis. They use a smaller amount of reagents and samples, hence, reducing the total cost of analysis. Therefore they have found application in a number of pharmaceutical and biomedical analysis. This review article focuses on the use and importance of pressurized and pressure-assisted capillary electrochromatography in pharmaceutical and biomedical analysis, taking into account types of detectors and capillaries used. Despite the fact that pressurized capillary electrochromatography and pressure assisted capillary electrochromatography offer many possibilities and have been available for over a dozen years, they are still underdevelopment and not fully explored.
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spelling doaj.art-74cd0f82903347ee83e13448f0bc49442022-12-21T18:35:36ZengSciendoCurrent Issues in Pharmacy and Medical Sciences2084-980X2300-66762019-06-01322929810.2478/cipms-2019-0018cipms-2019-0018An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?Trzebiatowski Michal Zmuda0Gwarda Radoslaw L.1Dzido Tadeusz H.2Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, PolandDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, PolandDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, PolandPharmaceutical analysis guarantees patient safety all over the world. Thus, continuous development of existing analytical techniques is still very important. Pressurized capillary electrochromatography and pressure-assisted capillary electrochromatography are hybrid separation techniques that combine the selectivity of liquid chromatography and the high separation efficiency of capillary electrophoresis. They use a smaller amount of reagents and samples, hence, reducing the total cost of analysis. Therefore they have found application in a number of pharmaceutical and biomedical analysis. This review article focuses on the use and importance of pressurized and pressure-assisted capillary electrochromatography in pharmaceutical and biomedical analysis, taking into account types of detectors and capillaries used. Despite the fact that pressurized capillary electrochromatography and pressure assisted capillary electrochromatography offer many possibilities and have been available for over a dozen years, they are still underdevelopment and not fully explored.https://doi.org/10.2478/cipms-2019-0018pressurized capillary electrochromatographypressure-assisted capillary electrochromatographypharmaceutical and biomedical analysisdrugs
spellingShingle Trzebiatowski Michal Zmuda
Gwarda Radoslaw L.
Dzido Tadeusz H.
An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
Current Issues in Pharmacy and Medical Sciences
pressurized capillary electrochromatography
pressure-assisted capillary electrochromatography
pharmaceutical and biomedical analysis
drugs
title An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
title_full An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
title_fullStr An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
title_full_unstemmed An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
title_short An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?
title_sort underestimated technique does pressurized and pressure assisted capillary electrochromatography have potential in drug and pharmacological active compounds analysis
topic pressurized capillary electrochromatography
pressure-assisted capillary electrochromatography
pharmaceutical and biomedical analysis
drugs
url https://doi.org/10.2478/cipms-2019-0018
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