Comparison of emissions across tobacco products: A slippery slope in tobacco control
In this narrative review, we highlight the challenges of comparing emissions from different tobacco products under controlled laboratory settings (using smoking/ vaping machines). We focus on tobacco products that generate inhalable smoke or aerosol, such as cigarettes, cigars, hookah, electronic ci...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2024-03-01
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| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | https://www.tobaccoinduceddiseases.org/Comparison-of-emissions-across-tobacco-products-A-slippery-slope-in-tobacco-control,183797,0,2.html |
| _version_ | 1797231954435768320 |
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| author | Ahmad El Hellani Ayomipo Adeniji Hanno C. Erythropel Qixin Wang Thomas Lamb Vladimir B. Mikheev Irfan Rahman Irina Stepanov Robert M. Strongin Theodore L. Wagener Marielle C. Brinkman |
| author_facet | Ahmad El Hellani Ayomipo Adeniji Hanno C. Erythropel Qixin Wang Thomas Lamb Vladimir B. Mikheev Irfan Rahman Irina Stepanov Robert M. Strongin Theodore L. Wagener Marielle C. Brinkman |
| author_sort | Ahmad El Hellani |
| collection | DOAJ |
| description | In this narrative review, we highlight the challenges of comparing emissions from
different tobacco products under controlled laboratory settings (using smoking/
vaping machines). We focus on tobacco products that generate inhalable smoke or
aerosol, such as cigarettes, cigars, hookah, electronic cigarettes, and heated tobacco
products. We discuss challenges associated with sample generation including
variability of smoking/vaping machines, lack of standardized adaptors that connect
smoking/vaping machines to different tobacco products, puffing protocols that are
not representative of actual use, and sample generation session length (minutes
or number of puffs) that depends on product characteristics. We also discuss the
challenges of physically characterizing and trapping emissions from products with
different aerosol characteristics. Challenges to analytical method development
are also covered, highlighting matrix effects, order of magnitude differences in
analyte levels, and the necessity of tailored quality control/quality assurance
measures. The review highlights two approaches in selecting emissions to monitor
across products, one focusing on toxicants that were detected and quantified with
optimized methods for combustible cigarettes, and the other looking for productspecific
toxicants using non-targeted analysis. The challenges of data reporting
and statistical analysis that allow meaningful comparison across products are also
discussed. We end the review by highlighting that even if the technical challenges
are overcome, emission comparison may obscure the absolute exposure from novel
products if we only focus on relative exposure compared to combustible products. |
| first_indexed | 2024-04-24T15:52:35Z |
| format | Article |
| id | doaj.art-74d419c167724a5f8330b840253c9c0f |
| institution | Directory Open Access Journal |
| issn | 1617-9625 |
| language | English |
| last_indexed | 2024-04-24T15:52:35Z |
| publishDate | 2024-03-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Tobacco Induced Diseases |
| spelling | doaj.art-74d419c167724a5f8330b840253c9c0f2024-04-01T10:16:49ZengEuropean PublishingTobacco Induced Diseases1617-96252024-03-0122March11310.18332/tid/183797183797Comparison of emissions across tobacco products: A slippery slope in tobacco controlAhmad El Hellani0https://orcid.org/0000-0002-1047-0597Ayomipo Adeniji1https://orcid.org/0000-0002-6355-2852Hanno C. Erythropel2https://orcid.org/0000-0003-3443-9794Qixin Wang3https://orcid.org/0000-0001-9051-8388Thomas Lamb4https://orcid.org/0000-0003-0607-0977Vladimir B. Mikheev5Irfan Rahman6https://orcid.org/0000-0003-2274-2454Irina Stepanov7https://orcid.org/0000-0001-5140-8944Robert M. Strongin8https://orcid.org/0000-0003-3777-8492Theodore L. Wagener9https://orcid.org/0000-0002-9072-228XMarielle C. Brinkman10https://orcid.org/0000-0002-4315-649XDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, United StatesDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, United StatesDepartment of Chemical and Environmental Engineering, School of Engineering & Applied Science, Yale University, New Haven, United StatesDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, United StatesDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, United StatesBattelle Public Health Center for Tobacco Research, Battelle Memorial Institute, Columbus, United StatesDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, United StatesDivision of Environmental Health Sciences, School of Public Health, University of Minnesota Twin Cities, Minneapolis, United StatesDepartment of Chemistry, Portland State University, Portland, United StatesCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, United StatesCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, United StatesIn this narrative review, we highlight the challenges of comparing emissions from different tobacco products under controlled laboratory settings (using smoking/ vaping machines). We focus on tobacco products that generate inhalable smoke or aerosol, such as cigarettes, cigars, hookah, electronic cigarettes, and heated tobacco products. We discuss challenges associated with sample generation including variability of smoking/vaping machines, lack of standardized adaptors that connect smoking/vaping machines to different tobacco products, puffing protocols that are not representative of actual use, and sample generation session length (minutes or number of puffs) that depends on product characteristics. We also discuss the challenges of physically characterizing and trapping emissions from products with different aerosol characteristics. Challenges to analytical method development are also covered, highlighting matrix effects, order of magnitude differences in analyte levels, and the necessity of tailored quality control/quality assurance measures. The review highlights two approaches in selecting emissions to monitor across products, one focusing on toxicants that were detected and quantified with optimized methods for combustible cigarettes, and the other looking for productspecific toxicants using non-targeted analysis. The challenges of data reporting and statistical analysis that allow meaningful comparison across products are also discussed. We end the review by highlighting that even if the technical challenges are overcome, emission comparison may obscure the absolute exposure from novel products if we only focus on relative exposure compared to combustible products.https://www.tobaccoinduceddiseases.org/Comparison-of-emissions-across-tobacco-products-A-slippery-slope-in-tobacco-control,183797,0,2.htmltobacco productsemission comparisonsample generationanalytical methodstoxicants |
| spellingShingle | Ahmad El Hellani Ayomipo Adeniji Hanno C. Erythropel Qixin Wang Thomas Lamb Vladimir B. Mikheev Irfan Rahman Irina Stepanov Robert M. Strongin Theodore L. Wagener Marielle C. Brinkman Comparison of emissions across tobacco products: A slippery slope in tobacco control Tobacco Induced Diseases tobacco products emission comparison sample generation analytical methods toxicants |
| title | Comparison of emissions across tobacco products: A slippery slope in tobacco control |
| title_full | Comparison of emissions across tobacco products: A slippery slope in tobacco control |
| title_fullStr | Comparison of emissions across tobacco products: A slippery slope in tobacco control |
| title_full_unstemmed | Comparison of emissions across tobacco products: A slippery slope in tobacco control |
| title_short | Comparison of emissions across tobacco products: A slippery slope in tobacco control |
| title_sort | comparison of emissions across tobacco products a slippery slope in tobacco control |
| topic | tobacco products emission comparison sample generation analytical methods toxicants |
| url | https://www.tobaccoinduceddiseases.org/Comparison-of-emissions-across-tobacco-products-A-slippery-slope-in-tobacco-control,183797,0,2.html |
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