Low-Dose-Rate Irradiation Suppresses the Expression of Cell Cycle-Related Genes, Resulting in Modification of Sensitivity to Anti-Cancer Drugs

Low-Dose-Rate Irradiation Suppresses the Expression of Cell Cycle-Related Genes, Resulting in Modification of Sensitivity to Anti-Cancer Drugs

The biological effects of low-dose-rate (LDR) radiation exposure in nuclear power plant accidents and medical uses of ionizing radiation (IR), although being a social concern, remain unclear. In this study, we evaluated the effects of LDR-IR on global gene expression in human cells and aimed to clar...

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Bibliographic Details
Main Authors: Kiichi Shimabukuro, Takahiro Fukazawa, Akinori Kanai, Hidehiko Kawai, Kengo Mekata, Nobuyuki Hirohashi, Naoya Kakimoto, Keiji Tanimoto
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
low-dose rate irradiation
hypoxia
<i>AURKB</i>
<i>FOXM1</i>
paclitaxel
Online Access:https://www.mdpi.com/2073-4409/11/3/501

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