Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining redox balance

Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining redox balance

Abstract Background Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs, including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility-enhancing properties. Hence, this study was designed to establish the effect of naringin on T2DM-induced test...

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Bibliographic Details
Main Authors: Kazeem Bidemi Okesina, Adeyemi Fatai Odetayo, Wale Johnson Adeyemi, Ayodeji Johnson Ajibare, Akeem Ayodeji Okesina, Luqman Aribidesi Olayaki
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Laboratory Animal Research
Subjects:
Testicular dysfunction
Xanthine oxidase/uric acid signaling
Redox balance
Diabetes mellitus
Naringin
Orange peel ethanolic extract
Online Access:https://doi.org/10.1186/s42826-024-00188-5

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