Glibenclamide Increases Nitric Oxide Levels and Decreases Oxidative Stress in an In Vitro Model of Preeclampsia

Glibenclamide Increases Nitric Oxide Levels and Decreases Oxidative Stress in an In Vitro Model of Preeclampsia

(1) Background: The bioavailability of nitric oxide (NO) and oxidative stress are important events related to the pathophysiology of preeclampsia (PE). In this present study, we aimed to evaluate the antioxidant effect of glibenclamide (GB) on the NO synthesis, oxidative stress, and antioxidant capa...

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Bibliographic Details
Main Authors: Priscila Rezeck Nunes, Thaina Omia Bueno Pereira, Mariana Bertozzi Matheus, Nubia Alves Grandini, Juliana Silva Siqueira, Camila Renata Correa, Joelcio Francisco Abbade, Valeria Cristina Sandrim
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Antioxidants
Subjects:
glibenclamide
preeclampsia
nitric oxide
reactive oxygen species
antioxidant capacity
HUVEC
Online Access:https://www.mdpi.com/2076-3921/11/8/1620

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