Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report

Abstract: Hemophagocytic syndrome (HLH), which occurs due to over activation and proliferation of the T-cells and macrophages resulting in massive hypercytokinemia, is a life threatening condition accompanied by systemic inflamatory diseases. HLH can develop secondary to malignancy, radical stress,...

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Main Authors: Esengül Keleş, Hamza Yazgan, Arzu Gebeşçe
Format: Article
Language:English
Published: Galenos Yayinevi 2013-12-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access:http://www.hasekidergisi.com/article_4711/Hemophagocytic-Syndrome-Which-Developed-During-Treatment-Of-Community-Acquired-Pneumonia-A-Case-Report
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author Esengül Keleş
Hamza Yazgan
Arzu Gebeşçe
author_facet Esengül Keleş
Hamza Yazgan
Arzu Gebeşçe
author_sort Esengül Keleş
collection DOAJ
description Abstract: Hemophagocytic syndrome (HLH), which occurs due to over activation and proliferation of the T-cells and macrophages resulting in massive hypercytokinemia, is a life threatening condition accompanied by systemic inflamatory diseases. HLH can develop secondary to malignancy, radical stress, metabolic diseases, immunodeficiency, and collagen tissue disorders as well as viral, bacterial and parasitic infections. A 6-year-old patient had progressive clinical and laboratory impairment during the treatment of community-acquired non-specific pneumonia. The diagnosis of HLH was established based on bone marrow aspiration which revealed macrophages which phagocytosed erythrocytes and leukocytes, and, thus, the treatment was started immediately. This case is reported due to the rarity of HLH developing during the treatment of pneumonia. (The Me¬di¬cal Bulletin of Haseki 2013;51:183-5)
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issn 1302-0072
2147-2688
language English
last_indexed 2024-04-10T10:13:31Z
publishDate 2013-12-01
publisher Galenos Yayinevi
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spelling doaj.art-74d875e76b9a4797bea9cbc2e361b1aa2023-02-15T16:22:01ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882013-12-0151418318510.4274/Haseki.1005Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case ReportEsengül Keleş0Hamza Yazgan1Arzu Gebeşçe2Fatih Üniversitesi Sema Uygulama ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, TürkiyeFatih Üniversitesi Sema Uygulama ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, TürkiyeFatih Üniversitesi Sema Uygulama ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, TürkiyeAbstract: Hemophagocytic syndrome (HLH), which occurs due to over activation and proliferation of the T-cells and macrophages resulting in massive hypercytokinemia, is a life threatening condition accompanied by systemic inflamatory diseases. HLH can develop secondary to malignancy, radical stress, metabolic diseases, immunodeficiency, and collagen tissue disorders as well as viral, bacterial and parasitic infections. A 6-year-old patient had progressive clinical and laboratory impairment during the treatment of community-acquired non-specific pneumonia. The diagnosis of HLH was established based on bone marrow aspiration which revealed macrophages which phagocytosed erythrocytes and leukocytes, and, thus, the treatment was started immediately. This case is reported due to the rarity of HLH developing during the treatment of pneumonia. (The Me¬di¬cal Bulletin of Haseki 2013;51:183-5)http://www.hasekidergisi.com/article_4711/Hemophagocytic-Syndrome-Which-Developed-During-Treatment-Of-Community-Acquired-Pneumonia-A-Case-ReportHemophagocyticlymphohistiocytosispneumonia
spellingShingle Esengül Keleş
Hamza Yazgan
Arzu Gebeşçe
Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
Haseki Tıp Bülteni
Hemophagocytic
lymphohistiocytosis
pneumonia
title Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
title_full Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
title_fullStr Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
title_full_unstemmed Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
title_short Hemophagocytic Syndrome Which Developed During Treatment of Community Acquired Pneumonia: A Case Report
title_sort hemophagocytic syndrome which developed during treatment of community acquired pneumonia a case report
topic Hemophagocytic
lymphohistiocytosis
pneumonia
url http://www.hasekidergisi.com/article_4711/Hemophagocytic-Syndrome-Which-Developed-During-Treatment-Of-Community-Acquired-Pneumonia-A-Case-Report
work_keys_str_mv AT esengulkeles hemophagocyticsyndromewhichdevelopedduringtreatmentofcommunityacquiredpneumoniaacasereport
AT hamzayazgan hemophagocyticsyndromewhichdevelopedduringtreatmentofcommunityacquiredpneumoniaacasereport
AT arzugebesce hemophagocyticsyndromewhichdevelopedduringtreatmentofcommunityacquiredpneumoniaacasereport