Acute Pulmonary Lesion: Pathogenesis and Morphology

Morphological studies were used to examine the lungs from 92 persons who had died from brain and concomitant injuries and massive blood loss and from 117 experimental animals (rats) in systemic circulatory disorders and vascular thrombosis of the pulmonary microcirculatory bed. The purpose of the st...

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Main Authors: A. M. Golubev, V. V. Moroz, G. N. Meshcheryakov, D. V. Lysenko
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2005-10-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/1215
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author A. M. Golubev
V. V. Moroz
G. N. Meshcheryakov
D. V. Lysenko
author_facet A. M. Golubev
V. V. Moroz
G. N. Meshcheryakov
D. V. Lysenko
author_sort A. M. Golubev
collection DOAJ
description Morphological studies were used to examine the lungs from 92 persons who had died from brain and concomitant injuries and massive blood loss and from 117 experimental animals (rats) in systemic circulatory disorders and vascular thrombosis of the pulmonary microcirculatory bed. The purpose of the study was to assess the nature, intensity, and developmental periods of the morphological signs characterizing acute pulmonary lesion. Disorders of circulation (including microcirculation), damages to bronchial and bronchiolar mucosae, the development of atelectases, dyst-electases, and focal emphysema were found to be early structural changes in injury and massive blood loss. Pulmonary edema and the signs of a systemic inflammatory reactions form within the first hours following injury and massive blood loss. Experimental studies confirm that microcirculatory disorders and individual traits play an important role in the development of acute pulmonary lesion.
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spelling doaj.art-74e0b903e5194c5bacd7d57219550d862023-03-13T09:32:45ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102005-10-011551210.15360/1813-9779-2005-5-5-121215Acute Pulmonary Lesion: Pathogenesis and MorphologyA. M. Golubev0V. V. Moroz1G. N. Meshcheryakov2D. V. Lysenko3ГУ НИИ общей реаниматологии РАМН, МоскваГУ НИИ общей реаниматологии РАМН, МоскваГУ НИИ общей реаниматологии РАМН, МоскваГУ НИИ общей реаниматологии РАМН, МоскваMorphological studies were used to examine the lungs from 92 persons who had died from brain and concomitant injuries and massive blood loss and from 117 experimental animals (rats) in systemic circulatory disorders and vascular thrombosis of the pulmonary microcirculatory bed. The purpose of the study was to assess the nature, intensity, and developmental periods of the morphological signs characterizing acute pulmonary lesion. Disorders of circulation (including microcirculation), damages to bronchial and bronchiolar mucosae, the development of atelectases, dyst-electases, and focal emphysema were found to be early structural changes in injury and massive blood loss. Pulmonary edema and the signs of a systemic inflammatory reactions form within the first hours following injury and massive blood loss. Experimental studies confirm that microcirculatory disorders and individual traits play an important role in the development of acute pulmonary lesion.https://www.reanimatology.com/rmt/article/view/1215
spellingShingle A. M. Golubev
V. V. Moroz
G. N. Meshcheryakov
D. V. Lysenko
Acute Pulmonary Lesion: Pathogenesis and Morphology
Общая реаниматология
title Acute Pulmonary Lesion: Pathogenesis and Morphology
title_full Acute Pulmonary Lesion: Pathogenesis and Morphology
title_fullStr Acute Pulmonary Lesion: Pathogenesis and Morphology
title_full_unstemmed Acute Pulmonary Lesion: Pathogenesis and Morphology
title_short Acute Pulmonary Lesion: Pathogenesis and Morphology
title_sort acute pulmonary lesion pathogenesis and morphology
url https://www.reanimatology.com/rmt/article/view/1215
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AT gnmeshcheryakov acutepulmonarylesionpathogenesisandmorphology
AT dvlysenko acutepulmonarylesionpathogenesisandmorphology