Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine
Reported vascular complications following mRNA-based COVID-19 vaccines are consisting of myocarditis, cerebral venous thrombosis, cerebral vascular thrombosis, and vaccine-induced thrombocytopenia. Here, we describe a case of a 49-year-old woman with left-sided pain above the middle common carotid a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Case Reports in Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2023/6679200 |
| _version_ | 1827079704496046080 |
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| author | Georgiana C. Sandu Gregor Weisser Stefan Krämer Matthias Reinhard |
| author_facet | Georgiana C. Sandu Gregor Weisser Stefan Krämer Matthias Reinhard |
| author_sort | Georgiana C. Sandu |
| collection | DOAJ |
| description | Reported vascular complications following mRNA-based COVID-19 vaccines are consisting of myocarditis, cerebral venous thrombosis, cerebral vascular thrombosis, and vaccine-induced thrombocytopenia. Here, we describe a case of a 49-year-old woman with left-sided pain above the middle common carotid artery (carotidynia) starting a few days after her second vaccination with an mRNA-based COVID-19 vaccine (Spikevax). Imaging was indicative of transient perivascular inflammation of the carotid artery (TIPIC) syndrome. The diagnostic workup for other immunologically mediated diseases was negative. The inflammation subsided after a course of prednisone and aspirin, and clinical symptoms vanished, but later mildly relapsed in the context of a viral upper respiratory tract infection other than SARS-CoV-2. Carotidynia because of TIPIC syndrome may present as an immunogenic side effect of the newly developed mRNA-based vaccinations against COVID-19. TIPIC syndrome should be considered in new-onset neck pain after vaccination. |
| first_indexed | 2024-03-11T23:15:35Z |
| format | Article |
| id | doaj.art-74e408bff2bd40798a75cffb6eac6269 |
| institution | Directory Open Access Journal |
| issn | 2090-6994 |
| language | English |
| last_indexed | 2025-03-20T02:49:48Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Vascular Medicine |
| spelling | doaj.art-74e408bff2bd40798a75cffb6eac62692024-10-03T07:27:36ZengHindawi LimitedCase Reports in Vascular Medicine2090-69942023-01-01202310.1155/2023/6679200Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 VaccineGeorgiana C. Sandu0Gregor Weisser1Stefan Krämer2Matthias Reinhard3Department of Neurology and Clinical NeurophysiologyCenter for Internal MedicineDepartment of Radiology and Nuclear MedicineDepartment of Neurology and Clinical NeurophysiologyReported vascular complications following mRNA-based COVID-19 vaccines are consisting of myocarditis, cerebral venous thrombosis, cerebral vascular thrombosis, and vaccine-induced thrombocytopenia. Here, we describe a case of a 49-year-old woman with left-sided pain above the middle common carotid artery (carotidynia) starting a few days after her second vaccination with an mRNA-based COVID-19 vaccine (Spikevax). Imaging was indicative of transient perivascular inflammation of the carotid artery (TIPIC) syndrome. The diagnostic workup for other immunologically mediated diseases was negative. The inflammation subsided after a course of prednisone and aspirin, and clinical symptoms vanished, but later mildly relapsed in the context of a viral upper respiratory tract infection other than SARS-CoV-2. Carotidynia because of TIPIC syndrome may present as an immunogenic side effect of the newly developed mRNA-based vaccinations against COVID-19. TIPIC syndrome should be considered in new-onset neck pain after vaccination.http://dx.doi.org/10.1155/2023/6679200 |
| spellingShingle | Georgiana C. Sandu Gregor Weisser Stefan Krämer Matthias Reinhard Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine Case Reports in Vascular Medicine |
| title | Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine |
| title_full | Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine |
| title_fullStr | Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine |
| title_full_unstemmed | Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine |
| title_short | Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine |
| title_sort | relapsing tipic syndrome after administration of an mrna based covid 19 vaccine |
| url | http://dx.doi.org/10.1155/2023/6679200 |
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