Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do
Abstract Background It’s necessary to analyze the related risk factors and complications of low cardiac output syndrome (LCOS) after operation in children with congenital heart disease (CHD), to elucidate the management strategy of LCOS. Methods CHD children admitted to the department of cardiology...
| Автори: | , , |
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| Формат: | Стаття |
| Мова: | English |
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BMC
2021-05-01
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| Серія: | Journal of Cardiothoracic Surgery |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s13019-021-01518-7 |
| _version_ | 1830508196057317376 |
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| author | Bangrong Song Haiming Dang Ran Dong |
| author_facet | Bangrong Song Haiming Dang Ran Dong |
| author_sort | Bangrong Song |
| collection | DOAJ |
| description | Abstract Background It’s necessary to analyze the related risk factors and complications of low cardiac output syndrome (LCOS) after operation in children with congenital heart disease (CHD), to elucidate the management strategy of LCOS. Methods CHD children admitted to the department of cardiology in our hospital from January 15, 2019 to October 31, 2020 were included. The personal and clinical data of CHD children with LCOS and without LCOS were collected and compared. Logistic regression analyses were conducted to identify the risk factors of postoperative LCOS. Besides, the complication and mortality of LCOS and no LCOS patients were compared. Results A total of 283 CHD patients were included, the incidence of postoperative LCOS in CHD patients was 12.37%. There were significant differences in the age, preoperative oxygen saturation, two-way ventricular shunt, duration of CPB and postoperative residual shunt between two groups (all p < 0.05). Logistic regression analyses indicated that age ≤ 4y(OR2.426, 95%CI1.044 ~ 4.149), preoperative oxygen saturation ≤ 93%(OR2.175, 95%CI1.182 ~ 5.033), two-way ventricular shunt (OR3.994, 95%CI1.247 ~ 6.797), duration of CPB ≥ 60 min(OR2.172, 95%CI1.002 ~ 4.309), postoperative residual shunt (OR1.487, 95%CI1.093 ~ 2.383) were the independent risk factors of LCOS in patients with CHD (all p < 0.05). There were significant differences in the acute liver injury, acute kidney injury, pulmonary infection, tracheotomy, duration of mechanical ventilation, length of ICU stay and mortality (all p < 0.05), no significant difference in the 24 h drainage was found(p = 0.095). Conclusion LCOS after CHD is common, more attentions should be paid to those patients with age ≤ 4y, preoperative oxygen saturation ≤ 93%, two-way ventricular shunt, duration of CPB ≥ 60 min, postoperative residual shunt to improve the prognosis of CHD patients. |
| first_indexed | 2024-12-22T01:15:53Z |
| format | Article |
| id | doaj.art-74e538c0f8ed4f3e94c6c803491cd77c |
| institution | Directory Open Access Journal |
| issn | 1749-8090 |
| language | English |
| last_indexed | 2024-12-22T01:15:53Z |
| publishDate | 2021-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj.art-74e538c0f8ed4f3e94c6c803491cd77c2022-12-21T18:43:52ZengBMCJournal of Cardiothoracic Surgery1749-80902021-05-011611610.1186/s13019-021-01518-7Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we doBangrong Song0Haiming Dang1Ran Dong2Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical UniversityAbstract Background It’s necessary to analyze the related risk factors and complications of low cardiac output syndrome (LCOS) after operation in children with congenital heart disease (CHD), to elucidate the management strategy of LCOS. Methods CHD children admitted to the department of cardiology in our hospital from January 15, 2019 to October 31, 2020 were included. The personal and clinical data of CHD children with LCOS and without LCOS were collected and compared. Logistic regression analyses were conducted to identify the risk factors of postoperative LCOS. Besides, the complication and mortality of LCOS and no LCOS patients were compared. Results A total of 283 CHD patients were included, the incidence of postoperative LCOS in CHD patients was 12.37%. There were significant differences in the age, preoperative oxygen saturation, two-way ventricular shunt, duration of CPB and postoperative residual shunt between two groups (all p < 0.05). Logistic regression analyses indicated that age ≤ 4y(OR2.426, 95%CI1.044 ~ 4.149), preoperative oxygen saturation ≤ 93%(OR2.175, 95%CI1.182 ~ 5.033), two-way ventricular shunt (OR3.994, 95%CI1.247 ~ 6.797), duration of CPB ≥ 60 min(OR2.172, 95%CI1.002 ~ 4.309), postoperative residual shunt (OR1.487, 95%CI1.093 ~ 2.383) were the independent risk factors of LCOS in patients with CHD (all p < 0.05). There were significant differences in the acute liver injury, acute kidney injury, pulmonary infection, tracheotomy, duration of mechanical ventilation, length of ICU stay and mortality (all p < 0.05), no significant difference in the 24 h drainage was found(p = 0.095). Conclusion LCOS after CHD is common, more attentions should be paid to those patients with age ≤ 4y, preoperative oxygen saturation ≤ 93%, two-way ventricular shunt, duration of CPB ≥ 60 min, postoperative residual shunt to improve the prognosis of CHD patients.https://doi.org/10.1186/s13019-021-01518-7Low cardiac output syndromeCongenital heart diseaseCardiologyPediatricSurgeryTreatment |
| spellingShingle | Bangrong Song Haiming Dang Ran Dong Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do Journal of Cardiothoracic Surgery Low cardiac output syndrome Congenital heart disease Cardiology Pediatric Surgery Treatment |
| title | Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do |
| title_full | Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do |
| title_fullStr | Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do |
| title_full_unstemmed | Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do |
| title_short | Analysis of risk factors of low cardiac output syndrome after congenital heart disease operation: what can we do |
| title_sort | analysis of risk factors of low cardiac output syndrome after congenital heart disease operation what can we do |
| topic | Low cardiac output syndrome Congenital heart disease Cardiology Pediatric Surgery Treatment |
| url | https://doi.org/10.1186/s13019-021-01518-7 |
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