Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma

AIM: To investigate the risk factors for malignant glaucoma occurrence after the surgery for primary angle-closure glaucoma, and to provide theoretical basis for the prevention and treatment of malignant glaucoma. <p>METHODS: The clinical data of 767 cases(965 eyes)of primary angle-closure gla...

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Main Authors: Hai-Yan Xian, Zhuo-Wei Wang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-01-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2018/1/201801039.pdf
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author Hai-Yan Xian
Zhuo-Wei Wang
author_facet Hai-Yan Xian
Zhuo-Wei Wang
author_sort Hai-Yan Xian
collection DOAJ
description AIM: To investigate the risk factors for malignant glaucoma occurrence after the surgery for primary angle-closure glaucoma, and to provide theoretical basis for the prevention and treatment of malignant glaucoma. <p>METHODS: The clinical data of 767 cases(965 eyes)of primary angle-closure glaucoma patients treated in our hospital from June 2012 to June 2016 were retrospectively analyzed. Patients were divided into two groups according to the postoperative investigation, patients with malignant glaucoma were divided into observation group, and 50 eyes without malignant glaucoma were randomly selected into control group. The gender, age, preoperative high intraocular pressure, chamber angle structure, axial length, crystal thickness, anterior chamber depth, diabetes mellitus, and hypertension of the patients in two groups were investigated. The risk factors were analyzed by single factor analysis, and the independent risk factors were analyzed by multivariate logistic regression analysis. <p>RESULTS: Malignant glaucoma occurred in 30 eyes after the surgery of primary angle closure glaucoma in 965 eyes with an incidence rate of 3.1%. The single factor analysis showed that age, preoperative high intraocular pressure, axial length, anterior chamber depth, lense thickness, complete closure of atrial angle were the risk factors of malignant glaucoma after primary angle closure glaucoma surgery, comparison between groups showed statistical significance(<i>P</i><0.05). Multivariate logistic regression analysis showed that age(<i>OR</i>=2.521, 95%<i>CI</i>=1.434-8.876), preoperative continuous high intraocular pressure(<i>OR</i>=2.483, 95%<i>CI </i>=2.123-11.543), axial length(<i>OR</i>=2.654, 95%<i>CI</i>=1.547-12.678), complete closure of atrial angle(<i>OR</i>=3.212, 95%<i>CI</i>=1.543-8.675)were the independent risk factors for malignant glaucoma after primary angle closure glaucoma surgery. <p>CONCLUSION: The incidence rate of malignant glaucoma after primary angle-closure glaucoma surgery in our hospital is 3.1%. Age, preoperative high intraocular pressure, axialc length, complete closure of atrial angle can rise the risk of occurring malignant glaucoma, so special attention shall be payed for this kind of patients.
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spelling doaj.art-74ecf483886c4ed69b0cde8d02032c052022-12-22T01:28:35ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-01-0118115615810.3980/j.issn.1672-5123.2018.1.39Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucomaHai-Yan Xian0Zhuo-Wei Wang1Department of Ophthalmology,the Hospital of Shunyi District Beijing, Beijing 101300, China;Department of Stomatology, the Hospital of Shunyi District Beijing, Beijing 101300, ChinaAIM: To investigate the risk factors for malignant glaucoma occurrence after the surgery for primary angle-closure glaucoma, and to provide theoretical basis for the prevention and treatment of malignant glaucoma. <p>METHODS: The clinical data of 767 cases(965 eyes)of primary angle-closure glaucoma patients treated in our hospital from June 2012 to June 2016 were retrospectively analyzed. Patients were divided into two groups according to the postoperative investigation, patients with malignant glaucoma were divided into observation group, and 50 eyes without malignant glaucoma were randomly selected into control group. The gender, age, preoperative high intraocular pressure, chamber angle structure, axial length, crystal thickness, anterior chamber depth, diabetes mellitus, and hypertension of the patients in two groups were investigated. The risk factors were analyzed by single factor analysis, and the independent risk factors were analyzed by multivariate logistic regression analysis. <p>RESULTS: Malignant glaucoma occurred in 30 eyes after the surgery of primary angle closure glaucoma in 965 eyes with an incidence rate of 3.1%. The single factor analysis showed that age, preoperative high intraocular pressure, axial length, anterior chamber depth, lense thickness, complete closure of atrial angle were the risk factors of malignant glaucoma after primary angle closure glaucoma surgery, comparison between groups showed statistical significance(<i>P</i><0.05). Multivariate logistic regression analysis showed that age(<i>OR</i>=2.521, 95%<i>CI</i>=1.434-8.876), preoperative continuous high intraocular pressure(<i>OR</i>=2.483, 95%<i>CI </i>=2.123-11.543), axial length(<i>OR</i>=2.654, 95%<i>CI</i>=1.547-12.678), complete closure of atrial angle(<i>OR</i>=3.212, 95%<i>CI</i>=1.543-8.675)were the independent risk factors for malignant glaucoma after primary angle closure glaucoma surgery. <p>CONCLUSION: The incidence rate of malignant glaucoma after primary angle-closure glaucoma surgery in our hospital is 3.1%. Age, preoperative high intraocular pressure, axialc length, complete closure of atrial angle can rise the risk of occurring malignant glaucoma, so special attention shall be payed for this kind of patients.http://ies.ijo.cn/cn_publish/2018/1/201801039.pdfprimary angle-closure glaucomatrabeculectomymalignant glaucomarisk factorsrisk factors
spellingShingle Hai-Yan Xian
Zhuo-Wei Wang
Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
Guoji Yanke Zazhi
primary angle-closure glaucoma
trabeculectomy
malignant glaucoma
risk factors
risk factors
title Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
title_full Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
title_fullStr Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
title_full_unstemmed Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
title_short Analysis on risk factors of malignant glaucoma after the surgery for primary angle-closure glaucoma
title_sort analysis on risk factors of malignant glaucoma after the surgery for primary angle closure glaucoma
topic primary angle-closure glaucoma
trabeculectomy
malignant glaucoma
risk factors
risk factors
url http://ies.ijo.cn/cn_publish/2018/1/201801039.pdf
work_keys_str_mv AT haiyanxian analysisonriskfactorsofmalignantglaucomaafterthesurgeryforprimaryangleclosureglaucoma
AT zhuoweiwang analysisonriskfactorsofmalignantglaucomaafterthesurgeryforprimaryangleclosureglaucoma