Decoding Cancer Evolution: Integrating Genetic and Non-Genetic Insights

Decoding Cancer Evolution: Integrating Genetic and Non-Genetic Insights

The development of cancer begins with cells transitioning from their multicellular nature to a state akin to unicellular organisms. This shift leads to a breakdown in the crucial regulators inherent to multicellularity, resulting in the emergence of diverse cancer cell subpopulations that have enhan...

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Bibliographic Details
Main Authors: Arghavan Ashouri, Chufan Zhang, Federico Gaiti
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Genes
Subjects:
cancer evolution
genetic alterations
epigenetics
tumour heterogeneity
clonal expansions
multicellularity
Online Access:https://www.mdpi.com/2073-4425/14/10/1856

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