Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients
Purpose: Acute appendicitis is the most frequent emergency procedure that requires acute surgical intervention. The mortality risk is higher in geriatric patients. There is not a single parameter to diagnose it easily and negative appendectomy is traditionally accepted however the operation itself c...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2017-09-01
|
| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/08941939.2016.1241324 |
| _version_ | 1827817285880905728 |
|---|---|
| author | Gulsen Cigsar Ali Cihat Yildirim Turgut Anuk Hakan Guzel Elnare Gunal Saygı Gulkan Burak Irem Caglar Bilgin |
| author_facet | Gulsen Cigsar Ali Cihat Yildirim Turgut Anuk Hakan Guzel Elnare Gunal Saygı Gulkan Burak Irem Caglar Bilgin |
| author_sort | Gulsen Cigsar |
| collection | DOAJ |
| description | Purpose: Acute appendicitis is the most frequent emergency procedure that requires acute surgical intervention. The mortality risk is higher in geriatric patients. There is not a single parameter to diagnose it easily and negative appendectomy is traditionally accepted however the operation itself can cause morbidity and mortality especially in elderly patients. The neutrophil-to-lymphocyte ratio is a predictor of acute inflammation and was recently studied for the diagnosis of AA. The aim of this study is to analyze the diagnostic value of NLR on positive appendectomy rates amongst geriatric and nongeriatric patients. Materials and Methods: 755 patients admitted to the emergency department, with abdominal pain who underwent urgent laparotomy after diagnosed as acute appendicitis. Patients' ages, genders, laboratory results, and intraoperative findings were collected. Geriatric patients were analyzed in group one, and nongeriatric patients were in group 2. Groups then sorted into subgroups by means of positive and negative appendectomies. Results: Although NLR was higher in positive appendectomy subgroup in group 1 it was not statistically significant. NLR could not independently predict positive appendectomy in geriatric patients. In group 2, male gender was significantly higher in the positive appendectomy group (p < 0.001). NLR was also significantly higher in the positive appendectomy group (p < 0.001). In group 2 NLR could independently predict positive appendectomy (p < 0.001). Conclusion: NLR could not predict positive appendectomy rates in the geriatric population but could in the nongeriatric patient group. To find the optimal NLR levels, prospective randomized studies are needed. |
| first_indexed | 2024-03-12T00:32:13Z |
| format | Article |
| id | doaj.art-74ef895531d849948b605eee026345e3 |
| institution | Directory Open Access Journal |
| issn | 0894-1939 1521-0553 |
| language | English |
| last_indexed | 2024-03-12T00:32:13Z |
| publishDate | 2017-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj.art-74ef895531d849948b605eee026345e32023-09-15T10:12:26ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532017-09-0130528529010.1080/08941939.2016.12413241241324Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric PatientsGulsen Cigsar0Ali Cihat Yildirim1Turgut Anuk2Hakan Guzel3Elnare Gunal4Saygı Gulkan5Burak Irem6Caglar Bilgin7Faculty of Medicine, Kafkas UniversityMinistry of Health Kars State HospitalFaculty of Medicine, Kafkas UniversityGeneral SurgeryFaculty of Medicine, Kafkas UniversityRepublic of Turkey Social Security InstitutionMinistry of Health Malkara State HospitalMinistry of Health Kanuni Sultan Suleyman Research and Education HospitalPurpose: Acute appendicitis is the most frequent emergency procedure that requires acute surgical intervention. The mortality risk is higher in geriatric patients. There is not a single parameter to diagnose it easily and negative appendectomy is traditionally accepted however the operation itself can cause morbidity and mortality especially in elderly patients. The neutrophil-to-lymphocyte ratio is a predictor of acute inflammation and was recently studied for the diagnosis of AA. The aim of this study is to analyze the diagnostic value of NLR on positive appendectomy rates amongst geriatric and nongeriatric patients. Materials and Methods: 755 patients admitted to the emergency department, with abdominal pain who underwent urgent laparotomy after diagnosed as acute appendicitis. Patients' ages, genders, laboratory results, and intraoperative findings were collected. Geriatric patients were analyzed in group one, and nongeriatric patients were in group 2. Groups then sorted into subgroups by means of positive and negative appendectomies. Results: Although NLR was higher in positive appendectomy subgroup in group 1 it was not statistically significant. NLR could not independently predict positive appendectomy in geriatric patients. In group 2, male gender was significantly higher in the positive appendectomy group (p < 0.001). NLR was also significantly higher in the positive appendectomy group (p < 0.001). In group 2 NLR could independently predict positive appendectomy (p < 0.001). Conclusion: NLR could not predict positive appendectomy rates in the geriatric population but could in the nongeriatric patient group. To find the optimal NLR levels, prospective randomized studies are needed.http://dx.doi.org/10.1080/08941939.2016.1241324geriatricsacute appendicitisneutrophillymphocyte |
| spellingShingle | Gulsen Cigsar Ali Cihat Yildirim Turgut Anuk Hakan Guzel Elnare Gunal Saygı Gulkan Burak Irem Caglar Bilgin Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients Journal of Investigative Surgery geriatrics acute appendicitis neutrophil lymphocyte |
| title | Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients |
| title_full | Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients |
| title_fullStr | Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients |
| title_full_unstemmed | Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients |
| title_short | Neutrophil to Lymphocyte Ratio on Appendectomy of Geriatric and Nongeriatric Patients |
| title_sort | neutrophil to lymphocyte ratio on appendectomy of geriatric and nongeriatric patients |
| topic | geriatrics acute appendicitis neutrophil lymphocyte |
| url | http://dx.doi.org/10.1080/08941939.2016.1241324 |
| work_keys_str_mv | AT gulsencigsar neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT alicihatyildirim neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT turgutanuk neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT hakanguzel neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT elnaregunal neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT saygıgulkan neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT burakirem neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients AT caglarbilgin neutrophiltolymphocyteratioonappendectomyofgeriatricandnongeriatricpatients |