Aggressive central giant cell granuloma – A case series with literature review

Central giant cell granuloma (CGCG) of the maxillofacial region is generally present as an asymptomatic slowly growing localised disease to aggressive neoplasm-like rapid expansive progression typically present with localised disease. It is an uncommon benign lesion with a low incidence that occurs...

Full description

Bibliographic Details
Main Authors: Manjula Hebbale, Versha Rani Giroh, Amit Mhapuskar, Darshan Hiremutt
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Online Access:http://www.jiaomr.in/article.asp?issn=0972-1363;year=2019;volume=31;issue=2;spage=171;epage=175;aulast=Hebbale
_version_ 1818541308640231424
author Manjula Hebbale
Versha Rani Giroh
Amit Mhapuskar
Darshan Hiremutt
author_facet Manjula Hebbale
Versha Rani Giroh
Amit Mhapuskar
Darshan Hiremutt
author_sort Manjula Hebbale
collection DOAJ
description Central giant cell granuloma (CGCG) of the maxillofacial region is generally present as an asymptomatic slowly growing localised disease to aggressive neoplasm-like rapid expansive progression typically present with localised disease. It is an uncommon benign lesion with a low incidence that occurs in the craniofacial region especially in jaw bones. It is a localised osteolytic lesion with varied biologic behavior of aggression which affects the jaw bones. There is much controversy regarding it arising as a result of trauma and its connection with the giant cell lesion seen in the long bones. As it is uncommon, it does not possess any characteristic clinical or radiologic features and resembles neoplasms; the diagnosis is initially some odontogenic or non-odontogenic neoplasm till a definitive histologic diagnosis of CGCG is made. We report five cases of an aggressive form of CGCG at different sites of involvement in the jaw bones.
first_indexed 2024-12-11T22:07:35Z
format Article
id doaj.art-74f276c60d5d4b15923f4aa61f165b83
institution Directory Open Access Journal
issn 0972-1363
language English
last_indexed 2024-12-11T22:07:35Z
publishDate 2019-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Indian Academy of Oral Medicine and Radiology
spelling doaj.art-74f276c60d5d4b15923f4aa61f165b832022-12-22T00:48:54ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632019-01-0131217117510.4103/jiaomr.jiaomr_45_19Aggressive central giant cell granuloma – A case series with literature reviewManjula HebbaleVersha Rani GirohAmit MhapuskarDarshan HiremuttCentral giant cell granuloma (CGCG) of the maxillofacial region is generally present as an asymptomatic slowly growing localised disease to aggressive neoplasm-like rapid expansive progression typically present with localised disease. It is an uncommon benign lesion with a low incidence that occurs in the craniofacial region especially in jaw bones. It is a localised osteolytic lesion with varied biologic behavior of aggression which affects the jaw bones. There is much controversy regarding it arising as a result of trauma and its connection with the giant cell lesion seen in the long bones. As it is uncommon, it does not possess any characteristic clinical or radiologic features and resembles neoplasms; the diagnosis is initially some odontogenic or non-odontogenic neoplasm till a definitive histologic diagnosis of CGCG is made. We report five cases of an aggressive form of CGCG at different sites of involvement in the jaw bones.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2019;volume=31;issue=2;spage=171;epage=175;aulast=HebbaleCalcitoningiant cellsgranulomamultilocular radiolucency
spellingShingle Manjula Hebbale
Versha Rani Giroh
Amit Mhapuskar
Darshan Hiremutt
Aggressive central giant cell granuloma – A case series with literature review
Journal of Indian Academy of Oral Medicine and Radiology
Calcitonin
giant cells
granuloma
multilocular radiolucency
title Aggressive central giant cell granuloma – A case series with literature review
title_full Aggressive central giant cell granuloma – A case series with literature review
title_fullStr Aggressive central giant cell granuloma – A case series with literature review
title_full_unstemmed Aggressive central giant cell granuloma – A case series with literature review
title_short Aggressive central giant cell granuloma – A case series with literature review
title_sort aggressive central giant cell granuloma a case series with literature review
topic Calcitonin
giant cells
granuloma
multilocular radiolucency
url http://www.jiaomr.in/article.asp?issn=0972-1363;year=2019;volume=31;issue=2;spage=171;epage=175;aulast=Hebbale
work_keys_str_mv AT manjulahebbale aggressivecentralgiantcellgranulomaacaseserieswithliteraturereview
AT versharanigiroh aggressivecentralgiantcellgranulomaacaseserieswithliteraturereview
AT amitmhapuskar aggressivecentralgiantcellgranulomaacaseserieswithliteraturereview
AT darshanhiremutt aggressivecentralgiantcellgranulomaacaseserieswithliteraturereview