Papilledema Due to Mirtazapine

Background: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor...

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Main Authors: Mehmet Emin Ceylan, Alper Evrensel, Gökçe Cömert
Format: Article
Language:English
Published: Galenos Publishing House 2016-06-01
Series:Balkan Medical Journal
Subjects:
Online Access:http://balkanmedicaljournal.org/text.php?lang=en&id=135
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author Mehmet Emin Ceylan
Alper Evrensel
Gökçe Cömert
author_facet Mehmet Emin Ceylan
Alper Evrensel
Gökçe Cömert
author_sort Mehmet Emin Ceylan
collection DOAJ
description Background: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor cerebri). Moreover, papilledema may also develop due to retinitis, vasculitis, Graves’ disease, hypertension, leukemia, lymphoma, diabetes mellitus and radiation. Case Report: In this article, a patient who developed papilledema while under treatment with mirtazapine (30 mg/day) for two years and recovered with termination of mirtazapine treatment was discussed to draw the attention of clinicians to this side effect of mirtazapine. Conclusion: Idiopathic intracranial hypertension and papilledema due to psychotropic drugs has been reported in the literature. Mirtazapine may rarely cause peripheral edema. However, papilledema due to mirtazapine has not been previously reported. Although papilledema is a very rare side effect of an antidepressant treatment, fundoscopic examinations of patients must be performed regularly.
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spelling doaj.art-74f633dfecd846ee8687160989ac106d2023-02-15T16:15:05ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312016-06-0133336336510.5152/balkanmedj.2016.150151Papilledema Due to MirtazapineMehmet Emin Ceylan0Alper Evrensel1Gökçe Cömert2Department of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyDepartment of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyDepartment of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyBackground: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor cerebri). Moreover, papilledema may also develop due to retinitis, vasculitis, Graves’ disease, hypertension, leukemia, lymphoma, diabetes mellitus and radiation. Case Report: In this article, a patient who developed papilledema while under treatment with mirtazapine (30 mg/day) for two years and recovered with termination of mirtazapine treatment was discussed to draw the attention of clinicians to this side effect of mirtazapine. Conclusion: Idiopathic intracranial hypertension and papilledema due to psychotropic drugs has been reported in the literature. Mirtazapine may rarely cause peripheral edema. However, papilledema due to mirtazapine has not been previously reported. Although papilledema is a very rare side effect of an antidepressant treatment, fundoscopic examinations of patients must be performed regularly.http://balkanmedicaljournal.org/text.php?lang=en&id=135Antidepressantmirtazapinepapilledemaside effect
spellingShingle Mehmet Emin Ceylan
Alper Evrensel
Gökçe Cömert
Papilledema Due to Mirtazapine
Balkan Medical Journal
Antidepressant
mirtazapine
papilledema
side effect
title Papilledema Due to Mirtazapine
title_full Papilledema Due to Mirtazapine
title_fullStr Papilledema Due to Mirtazapine
title_full_unstemmed Papilledema Due to Mirtazapine
title_short Papilledema Due to Mirtazapine
title_sort papilledema due to mirtazapine
topic Antidepressant
mirtazapine
papilledema
side effect
url http://balkanmedicaljournal.org/text.php?lang=en&id=135
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AT alperevrensel papilledemaduetomirtazapine
AT gokcecomert papilledemaduetomirtazapine