Papilledema Due to Mirtazapine
Background: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Galenos Publishing House
2016-06-01
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Series: | Balkan Medical Journal |
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Online Access: | http://balkanmedicaljournal.org/text.php?lang=en&id=135 |
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author | Mehmet Emin Ceylan Alper Evrensel Gökçe Cömert |
author_facet | Mehmet Emin Ceylan Alper Evrensel Gökçe Cömert |
author_sort | Mehmet Emin Ceylan |
collection | DOAJ |
description | Background: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor cerebri). Moreover, papilledema may also develop due to retinitis, vasculitis, Graves’ disease, hypertension, leukemia, lymphoma, diabetes mellitus and radiation.
Case Report: In this article, a patient who developed papilledema while under treatment with mirtazapine (30 mg/day) for two years and recovered with termination of mirtazapine treatment was discussed to draw the attention of clinicians to this side effect of mirtazapine.
Conclusion: Idiopathic intracranial hypertension and papilledema due to psychotropic drugs has been reported in the literature. Mirtazapine may rarely cause peripheral edema. However, papilledema due to mirtazapine has not been previously reported. Although papilledema is a very rare side effect of an antidepressant treatment, fundoscopic examinations of patients must be performed regularly. |
first_indexed | 2024-04-10T12:27:38Z |
format | Article |
id | doaj.art-74f633dfecd846ee8687160989ac106d |
institution | Directory Open Access Journal |
issn | 2146-3123 2146-3131 |
language | English |
last_indexed | 2024-04-10T12:27:38Z |
publishDate | 2016-06-01 |
publisher | Galenos Publishing House |
record_format | Article |
series | Balkan Medical Journal |
spelling | doaj.art-74f633dfecd846ee8687160989ac106d2023-02-15T16:15:05ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312016-06-0133336336510.5152/balkanmedj.2016.150151Papilledema Due to MirtazapineMehmet Emin Ceylan0Alper Evrensel1Gökçe Cömert2Department of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyDepartment of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyDepartment of Psychology, Üsküdar University School of Humanities and Social Sciences, İstanbul, TurkeyBackground: Mirtazapine is a tetracyclic antidepressant that enhances both noradrenergic and serotonergic transmission. The most common cause of papilledema is increased intracranial pressure due to brain tumor. Also it may occur as a result of idiopathic intracranial hypertension (IIH, pseudo tumor cerebri). Moreover, papilledema may also develop due to retinitis, vasculitis, Graves’ disease, hypertension, leukemia, lymphoma, diabetes mellitus and radiation. Case Report: In this article, a patient who developed papilledema while under treatment with mirtazapine (30 mg/day) for two years and recovered with termination of mirtazapine treatment was discussed to draw the attention of clinicians to this side effect of mirtazapine. Conclusion: Idiopathic intracranial hypertension and papilledema due to psychotropic drugs has been reported in the literature. Mirtazapine may rarely cause peripheral edema. However, papilledema due to mirtazapine has not been previously reported. Although papilledema is a very rare side effect of an antidepressant treatment, fundoscopic examinations of patients must be performed regularly.http://balkanmedicaljournal.org/text.php?lang=en&id=135Antidepressantmirtazapinepapilledemaside effect |
spellingShingle | Mehmet Emin Ceylan Alper Evrensel Gökçe Cömert Papilledema Due to Mirtazapine Balkan Medical Journal Antidepressant mirtazapine papilledema side effect |
title | Papilledema Due to Mirtazapine |
title_full | Papilledema Due to Mirtazapine |
title_fullStr | Papilledema Due to Mirtazapine |
title_full_unstemmed | Papilledema Due to Mirtazapine |
title_short | Papilledema Due to Mirtazapine |
title_sort | papilledema due to mirtazapine |
topic | Antidepressant mirtazapine papilledema side effect |
url | http://balkanmedicaljournal.org/text.php?lang=en&id=135 |
work_keys_str_mv | AT mehmeteminceylan papilledemaduetomirtazapine AT alperevrensel papilledemaduetomirtazapine AT gokcecomert papilledemaduetomirtazapine |