PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE
Protein-losing enteropathy (PLE) represents an abnormal protein loss at the level of the digestive tract mucosa, being in most of the cases secondary to other gastrointestinal or extraintestinal pathologies. Nevertheless, there also are primary causes, genetic ones associated with PLE. We present th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2017-03-01
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| Series: | Romanian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | https://revistemedicale.amaltea.ro/Romanian_Journal_of_INFECTIOUS_DISEASES/Revista_Romana_de_BOLI_INFECTIOASE-2017-Nr.1/RJID_2017_1_EN_Art-04.pdf |
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| author | Lorena Elena Melit Cristina Oana Marginean Andreea Dinca Raluca Damian Cristian Dan Marginean |
| author_facet | Lorena Elena Melit Cristina Oana Marginean Andreea Dinca Raluca Damian Cristian Dan Marginean |
| author_sort | Lorena Elena Melit |
| collection | DOAJ |
| description | Protein-losing enteropathy (PLE) represents an abnormal protein loss at the level of the digestive tract mucosa, being in most of the cases secondary to other gastrointestinal or extraintestinal pathologies. Nevertheless, there also are primary causes, genetic ones associated with PLE. We present the case of a small
female child, 1 year and 1 month-old, with a history of infectious enterocolitis determined by Escherichia coli
enteropathogenic, who presented palpebral edemas, especially in the morning for approximately 1 week.
The laboratory tests revealed hypoalbuminemia, type A and G hypogammaglobulinemia, leukocytosis with
eosinophilia, and anemia. The test for the detection of occult hemorrhages from feces was positive, likewise
the fecal calprotectin and level of alpha-1 antitrypsin. We identified also allergy to cow’s milk protein, which
we interpreted as being secondary to the intestinal pathology. Thus, we established the diagnosis of proteinlosing enteropathy after an episode of acute enterocolitis caused by E. coli enteropathogenic, and we administered substitutive treatment with human albumin and steroids, with favorable evolution. The particularity of
the case consists in diagnosing a severe case of protein-losing enteropathy in a small child, with palpebral
edema, predominantly during the morning, and decreased levels of serum albumin, after an episode of acute
enterocolitis caused by E. coli enteropathogenic, which remitted without etiologic treatment. |
| first_indexed | 2024-12-17T21:16:15Z |
| format | Article |
| id | doaj.art-74f7faa0c7a9432dad9603339d1b8800 |
| institution | Directory Open Access Journal |
| issn | 1454-3389 2069-6051 |
| language | English |
| last_indexed | 2024-12-17T21:16:15Z |
| publishDate | 2017-03-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Infectious Diseases |
| spelling | doaj.art-74f7faa0c7a9432dad9603339d1b88002022-12-21T21:32:20ZengAmaltea Medical Publishing HouseRomanian Journal of Infectious Diseases1454-33892069-60512017-03-01201263010.37897/RJID.2017.1.4PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURELorena Elena Melit0Cristina Oana Marginean1Andreea Dinca2Raluca Damian3Cristian Dan Marginean4Pediatrics Clinic 1, Tg. Mures; University of Medicine and Pharmacy, Tg.MuresPediatrics Clinic 1, Tg. Mures; University of Medicine and Pharmacy, Tg.MuresPediatrics Clinic 1, Tg. MuresNeonatology Clinic 1, Tg. MuresUniversity of Medicine and Pharmacy, Tg.MuresProtein-losing enteropathy (PLE) represents an abnormal protein loss at the level of the digestive tract mucosa, being in most of the cases secondary to other gastrointestinal or extraintestinal pathologies. Nevertheless, there also are primary causes, genetic ones associated with PLE. We present the case of a small female child, 1 year and 1 month-old, with a history of infectious enterocolitis determined by Escherichia coli enteropathogenic, who presented palpebral edemas, especially in the morning for approximately 1 week. The laboratory tests revealed hypoalbuminemia, type A and G hypogammaglobulinemia, leukocytosis with eosinophilia, and anemia. The test for the detection of occult hemorrhages from feces was positive, likewise the fecal calprotectin and level of alpha-1 antitrypsin. We identified also allergy to cow’s milk protein, which we interpreted as being secondary to the intestinal pathology. Thus, we established the diagnosis of proteinlosing enteropathy after an episode of acute enterocolitis caused by E. coli enteropathogenic, and we administered substitutive treatment with human albumin and steroids, with favorable evolution. The particularity of the case consists in diagnosing a severe case of protein-losing enteropathy in a small child, with palpebral edema, predominantly during the morning, and decreased levels of serum albumin, after an episode of acute enterocolitis caused by E. coli enteropathogenic, which remitted without etiologic treatment.https://revistemedicale.amaltea.ro/Romanian_Journal_of_INFECTIOUS_DISEASES/Revista_Romana_de_BOLI_INFECTIOASE-2017-Nr.1/RJID_2017_1_EN_Art-04.pdfprotein-losing enteropathyenterocolitisescherichia coli enteropathogenicchild |
| spellingShingle | Lorena Elena Melit Cristina Oana Marginean Andreea Dinca Raluca Damian Cristian Dan Marginean PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE Romanian Journal of Infectious Diseases protein-losing enteropathy enterocolitis escherichia coli enteropathogenic child |
| title | PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE |
| title_full | PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE |
| title_fullStr | PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE |
| title_full_unstemmed | PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE |
| title_short | PROTEIN-LOSING ENTEROPATHY AFTER INFECTIOUS ENTEROCOLITIS IN CHILD – A CASE REPORT AND A REVIEW OF THE LITERATURE |
| title_sort | protein losing enteropathy after infectious enterocolitis in child a case report and a review of the literature |
| topic | protein-losing enteropathy enterocolitis escherichia coli enteropathogenic child |
| url | https://revistemedicale.amaltea.ro/Romanian_Journal_of_INFECTIOUS_DISEASES/Revista_Romana_de_BOLI_INFECTIOASE-2017-Nr.1/RJID_2017_1_EN_Art-04.pdf |
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