Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia
Introduction. The leading role of the human papillomavirus in the etiopathogenesis of malignant neoplasms of some localizations is generally recognized. Vaccines that are used in the world and in Russia for the prevention of papillomavirus infection create the basis for the elimination of diseases a...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Central Research Institute for Epidemiology
2023-04-01
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| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.crie.ru/jour/article/viewFile/7278/856 |
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| author | Liudmila V. Lyalina Dmitry V. Kholopov Arkady V. Yazenok Valentin V. Khizha Eldar E. Topuzov Evgeny V. Kasatkin Evgeny A. Goryaev Tatiana G. Zadorkina Zhanna R. Molchanova |
| author_facet | Liudmila V. Lyalina Dmitry V. Kholopov Arkady V. Yazenok Valentin V. Khizha Eldar E. Topuzov Evgeny V. Kasatkin Evgeny A. Goryaev Tatiana G. Zadorkina Zhanna R. Molchanova |
| author_sort | Liudmila V. Lyalina |
| collection | DOAJ |
| description | Introduction. The leading role of the human papillomavirus in the etiopathogenesis of malignant neoplasms of some localizations is generally recognized. Vaccines that are used in the world and in Russia for the prevention of papillomavirus infection create the basis for the elimination of diseases associated with the human papillomavirus in the future.
The aim of the study is to determine the regional, gender and age-specific features of cancers associated with the human papillomavirus to substantiate the development of a unified system of epidemiological surveillance and vaccination.
Materials and methods. The retrospective epidemiological analysis of the incidence of cancers associated with the human papillomavirus and mortality due to these neoplasms in the regions of the North-Western Federal District of Russia in 20112020 was carried out based on data from Statistic Form 7 "Information on malignant neoplasms" and the Population cancer Registers of St. Petersburg (13,117 cases), Leningrad region (3204 cases) and the Kaliningrad region (2898 cases).
Results. In the structure of cancers associated with the human papillomavirus in St. Petersburg, Leningrad and Kaliningrad regions, more than 90% of men had tumors of the oral cavity, oropharynx and larynx, more than 60% of women had cervical cancer. Regional and age-specific features of the incidence of cervical cancer and mortality from this pathology have been established. Statistically significant differences in the incidence of cancer of the head and neck, anus and anal canal in different age groups of the male and female population were revealed.
Conclusion. As a result of the study, regional, gender and age-specific features of the incidence of human papillomavirus-associated malignant neoplasms in the North-West of Russia were established. These data should be used to develop a system of epidemiological surveillance of papillomavirus infection and vaccination program. |
| first_indexed | 2024-03-11T10:51:05Z |
| format | Article |
| id | doaj.art-74f7ff52382e4c8589d6ef27a4cfe7ad |
| institution | Directory Open Access Journal |
| issn | 0372-9311 2686-7613 |
| language | Russian |
| last_indexed | 2024-03-11T10:51:05Z |
| publishDate | 2023-04-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Журнал микробиологии, эпидемиологии и иммунобиологии |
| spelling | doaj.art-74f7ff52382e4c8589d6ef27a4cfe7ad2023-11-13T17:19:52ZrusCentral Research Institute for EpidemiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-76132023-04-011001526410.36233/0372-9311-327872Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West RussiaLiudmila V. Lyalina0https://orcid.org/0000-0001-9921-3505Dmitry V. Kholopov1https://orcid.org/0000-0002-1268-6172Arkady V. Yazenok2https://orcid.org/0000-0002-1334-8191Valentin V. Khizha3https://orcid.org/0000-0002-4218-0228Eldar E. Topuzov4https://orcid.org/0000-0002-1700-1128Evgeny V. Kasatkin5https://orcid.org/0000-0003-0029-7150Evgeny A. Goryaev6https://orcid.org/0000-0001-6842-7201Tatiana G. Zadorkina7https://orcid.org/0000-0002-2905-2635Zhanna R. Molchanova8https://orcid.org/0000-0002-2704-7832St. Petersburg Pasteur InstituteSt. Petersburg Pasteur InstituteMedical information and analytical centerMedical information and analytical centerSaint-Petersburg City Oncology ClinicSkin and venereological dispensary No. 8, St. PetersburgCenter for the Prevention and Control of AIDS and Infectious Diseases of the Leningrad RegionCenter for Specialized Types of Medical Care of the Kaliningrad regionDepartment of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare in the Kaliningrad RegionIntroduction. The leading role of the human papillomavirus in the etiopathogenesis of malignant neoplasms of some localizations is generally recognized. Vaccines that are used in the world and in Russia for the prevention of papillomavirus infection create the basis for the elimination of diseases associated with the human papillomavirus in the future. The aim of the study is to determine the regional, gender and age-specific features of cancers associated with the human papillomavirus to substantiate the development of a unified system of epidemiological surveillance and vaccination. Materials and methods. The retrospective epidemiological analysis of the incidence of cancers associated with the human papillomavirus and mortality due to these neoplasms in the regions of the North-Western Federal District of Russia in 20112020 was carried out based on data from Statistic Form 7 "Information on malignant neoplasms" and the Population cancer Registers of St. Petersburg (13,117 cases), Leningrad region (3204 cases) and the Kaliningrad region (2898 cases). Results. In the structure of cancers associated with the human papillomavirus in St. Petersburg, Leningrad and Kaliningrad regions, more than 90% of men had tumors of the oral cavity, oropharynx and larynx, more than 60% of women had cervical cancer. Regional and age-specific features of the incidence of cervical cancer and mortality from this pathology have been established. Statistically significant differences in the incidence of cancer of the head and neck, anus and anal canal in different age groups of the male and female population were revealed. Conclusion. As a result of the study, regional, gender and age-specific features of the incidence of human papillomavirus-associated malignant neoplasms in the North-West of Russia were established. These data should be used to develop a system of epidemiological surveillance of papillomavirus infection and vaccination program.https://microbiol.crie.ru/jour/article/viewFile/7278/856human papillomaviruscancerregionalgender and age features in north-west of russiamorbiditymortality |
| spellingShingle | Liudmila V. Lyalina Dmitry V. Kholopov Arkady V. Yazenok Valentin V. Khizha Eldar E. Topuzov Evgeny V. Kasatkin Evgeny A. Goryaev Tatiana G. Zadorkina Zhanna R. Molchanova Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia Журнал микробиологии, эпидемиологии и иммунобиологии human papillomavirus cancer regional gender and age features in north-west of russia morbidity mortality |
| title | Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia |
| title_full | Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia |
| title_fullStr | Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia |
| title_full_unstemmed | Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia |
| title_short | Clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of North-West Russia |
| title_sort | clinical and epidemiological characteristics of cancers associated with human papillomavirus in the regions of north west russia |
| topic | human papillomavirus cancer regional gender and age features in north-west of russia morbidity mortality |
| url | https://microbiol.crie.ru/jour/article/viewFile/7278/856 |
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