Bioelectrocatalysis with a palladium membrane reactor

Enzymatic catalysis requires cofactors such as NAD(P)H, whose regeneration is currently accomplished via secondary enzymes or electrolytic cell. Here, the authors report an electrochemical method of cofactors regeneration without supporting enzymes or mediators, nor formation of NAD2 dimers.

Bibliographic Details
Main Authors: Aiko Kurimoto, Seyed A. Nasseri, Camden Hunt, Mike Rooney, David J. Dvorak, Natalie E. LeSage, Ryan P. Jansonius, Stephen G. Withers, Curtis P. Berlinguette
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37257-7
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author Aiko Kurimoto
Seyed A. Nasseri
Camden Hunt
Mike Rooney
David J. Dvorak
Natalie E. LeSage
Ryan P. Jansonius
Stephen G. Withers
Curtis P. Berlinguette
author_facet Aiko Kurimoto
Seyed A. Nasseri
Camden Hunt
Mike Rooney
David J. Dvorak
Natalie E. LeSage
Ryan P. Jansonius
Stephen G. Withers
Curtis P. Berlinguette
author_sort Aiko Kurimoto
collection DOAJ
description Enzymatic catalysis requires cofactors such as NAD(P)H, whose regeneration is currently accomplished via secondary enzymes or electrolytic cell. Here, the authors report an electrochemical method of cofactors regeneration without supporting enzymes or mediators, nor formation of NAD2 dimers.
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spelling doaj.art-74fad450e4624111b4219dd8125a91152023-04-03T05:33:03ZengNature PortfolioNature Communications2041-17232023-03-0114111010.1038/s41467-023-37257-7Bioelectrocatalysis with a palladium membrane reactorAiko Kurimoto0Seyed A. Nasseri1Camden Hunt2Mike Rooney3David J. Dvorak4Natalie E. LeSage5Ryan P. Jansonius6Stephen G. Withers7Curtis P. Berlinguette8Department of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaStewart Blusson Quantum Matter Institute, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaDepartment of Chemistry, The University of British ColumbiaEnzymatic catalysis requires cofactors such as NAD(P)H, whose regeneration is currently accomplished via secondary enzymes or electrolytic cell. Here, the authors report an electrochemical method of cofactors regeneration without supporting enzymes or mediators, nor formation of NAD2 dimers.https://doi.org/10.1038/s41467-023-37257-7
spellingShingle Aiko Kurimoto
Seyed A. Nasseri
Camden Hunt
Mike Rooney
David J. Dvorak
Natalie E. LeSage
Ryan P. Jansonius
Stephen G. Withers
Curtis P. Berlinguette
Bioelectrocatalysis with a palladium membrane reactor
Nature Communications
title Bioelectrocatalysis with a palladium membrane reactor
title_full Bioelectrocatalysis with a palladium membrane reactor
title_fullStr Bioelectrocatalysis with a palladium membrane reactor
title_full_unstemmed Bioelectrocatalysis with a palladium membrane reactor
title_short Bioelectrocatalysis with a palladium membrane reactor
title_sort bioelectrocatalysis with a palladium membrane reactor
url https://doi.org/10.1038/s41467-023-37257-7
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