Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster.

Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster.

In all animals managing the size of individual meals and frequency of feeding is crucial for metabolic homeostasis. In the current study we demonstrate that the noradrenalin analogue octopamine and the cholecystokinin (CCK) homologue Drosulfakinin (Dsk) function downstream of TfAP-2 and Tiwaz (Twz)...

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Main Authors: Michael J Williams, Philip Goergen, Jayasimman Rajendran, Galina Zheleznyakova, Maria G Hägglund, Emelie Perland, Sonchita Bagchi, Argyro Kalogeropoulou, Zaid Khan, Robert Fredriksson, Helgi B Schiöth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4154645?pdf=render

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