High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips
Background: Acrylamide is a known carcinogenic product that has been found among the substances such as potato chips which to be processed under the heat-treatment. In order to extract amounts of acrylamide from fried chips in market, an ultrasound-assisted liquid– liquid extraction (UA-LLE) techniq...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tabriz University of Medical Sciences
2019-12-01
|
| Series: | Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ps.tbzmed.ac.ir/PDF/Pharm-32795 |
| _version_ | 1818918543200092160 |
|---|---|
| author | Maryam Ghalebi Samin Hamidi Mahboob Nemati |
| author_facet | Maryam Ghalebi Samin Hamidi Mahboob Nemati |
| author_sort | Maryam Ghalebi |
| collection | DOAJ |
| description | Background: Acrylamide is a known carcinogenic product that has been found among the substances such as potato chips which to be processed under the heat-treatment. In order to extract amounts of acrylamide from fried chips in market, an ultrasound-assisted liquid– liquid extraction (UA-LLE) technique is proposed. The UA-LLE coupled LLE and ultrasonication in a single step. Methods: Chips samples were dissolved in an extracting organic solvent using ultrasonication to prompt transferring of acrylamide into the organic phase. As a result, the extraction time and process efficiency were significantly enhanced through increasing the collision power and mass transfer between grounded chips and organic phase. Results: Important parameters affecting the extraction efficiency such as kind of organic solvent and its volume, re-dissolving solvent and pH were optimized. This newly proposed method has been applied to determine the trace acrylamide in potato chips samples purchased from local market. Conclusion: UA-LLE is a handy, economic and time-saving method, with high extraction yield (over 103% average recovery) and good precision (lower than 15% relative standard deviation, RSD). Most importantly, it seems this method to be an ideal pre-treatment method for the extraction of acrylamide in food matrix in food quality control laboratories. |
| first_indexed | 2024-12-20T00:51:38Z |
| format | Article |
| id | doaj.art-74fc19c5ad764e909036e963f76d4afa |
| institution | Directory Open Access Journal |
| issn | 2383-2886 |
| language | English |
| last_indexed | 2024-12-20T00:51:38Z |
| publishDate | 2019-12-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Pharmaceutical Sciences |
| spelling | doaj.art-74fc19c5ad764e909036e963f76d4afa2022-12-21T19:59:13ZengTabriz University of Medical SciencesPharmaceutical Sciences2383-28862019-12-0125433834410.15171/PS.2019.42Pharm-32795High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato ChipsMaryam Ghalebi0Samin Hamidi1Mahboob Nemati2Pharmaceutical Analysis Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.Food and Drug Safety Research Center, Tabriz University of Medical Science, Tabriz 51664, Iran.Food and Drug Safety Research Center, Tabriz University of Medical Science, Tabriz 51664, Iran.Background: Acrylamide is a known carcinogenic product that has been found among the substances such as potato chips which to be processed under the heat-treatment. In order to extract amounts of acrylamide from fried chips in market, an ultrasound-assisted liquid– liquid extraction (UA-LLE) technique is proposed. The UA-LLE coupled LLE and ultrasonication in a single step. Methods: Chips samples were dissolved in an extracting organic solvent using ultrasonication to prompt transferring of acrylamide into the organic phase. As a result, the extraction time and process efficiency were significantly enhanced through increasing the collision power and mass transfer between grounded chips and organic phase. Results: Important parameters affecting the extraction efficiency such as kind of organic solvent and its volume, re-dissolving solvent and pH were optimized. This newly proposed method has been applied to determine the trace acrylamide in potato chips samples purchased from local market. Conclusion: UA-LLE is a handy, economic and time-saving method, with high extraction yield (over 103% average recovery) and good precision (lower than 15% relative standard deviation, RSD). Most importantly, it seems this method to be an ideal pre-treatment method for the extraction of acrylamide in food matrix in food quality control laboratories.https://ps.tbzmed.ac.ir/PDF/Pharm-32795acrylamideliquid–liquid extractionpotato chipsultrasound |
| spellingShingle | Maryam Ghalebi Samin Hamidi Mahboob Nemati High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips Pharmaceutical Sciences acrylamide liquid–liquid extraction potato chips ultrasound |
| title | High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips |
| title_full | High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips |
| title_fullStr | High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips |
| title_full_unstemmed | High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips |
| title_short | High-Performance Liquid Chromatography Determination of Acrylamide after Its Extraction from Potato Chips |
| title_sort | high performance liquid chromatography determination of acrylamide after its extraction from potato chips |
| topic | acrylamide liquid–liquid extraction potato chips ultrasound |
| url | https://ps.tbzmed.ac.ir/PDF/Pharm-32795 |
| work_keys_str_mv | AT maryamghalebi highperformanceliquidchromatographydeterminationofacrylamideafteritsextractionfrompotatochips AT saminhamidi highperformanceliquidchromatographydeterminationofacrylamideafteritsextractionfrompotatochips AT mahboobnemati highperformanceliquidchromatographydeterminationofacrylamideafteritsextractionfrompotatochips |