Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2

Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2

Steroid 5-alpha reductases (SRD5As) are responsible for the conversion of testosterone to dihydrotestosterone, a potent androgen, which is the aetiologic factor of androgenetic alopecia. This study aimed to compare the <i>SRD5A</i> gene expression suppression activity exerted by Thai ric...

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Bibliographic Details
Main Authors: Chiranan Khantham, Wipawadee Yooin, Korawan Sringarm, Sarana Rose Sommano, Supat Jiranusornkul, Francisco David Carmona, Wutigri Nimlamool, Pensak Jantrawut, Pornchai Rachtanapun, Warintorn Ruksiriwanich
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biology
Subjects:
5α-reductase
androgenetic alopecia
rice bran
tocopherol
SRD5A2
molecular dynamics
Online Access:https://www.mdpi.com/2079-7737/10/4/319

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