Granulomatosis with polyangiitis
Granulomatosis with polyangiitis is a small and medium vessel vasculitis. It may affect any organ system. Neurological involvement, though less frequent, mostly manifests as peripheral neuropathy. Central nervous system (CNS) involvement as autoimmune cerebritis is rare but may be devastating. We re...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bangabandhu Sheikh Mujib Medical University
2016-12-01
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| Series: | Bangabandhu Sheikh Mujib Medical University Journal |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BSMMUJ/article/view/30332 |
| _version_ | 1818509002688954368 |
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| author | Zubayer Ahmad Sadiqa Tuqan Mirza Nazimuddin Rama Biswas Anindita Roy |
| author_facet | Zubayer Ahmad Sadiqa Tuqan Mirza Nazimuddin Rama Biswas Anindita Roy |
| author_sort | Zubayer Ahmad |
| collection | DOAJ |
| description | Granulomatosis with polyangiitis is a small and medium vessel vasculitis. It may affect any organ system. Neurological involvement, though less frequent, mostly manifests as peripheral neuropathy. Central nervous system (CNS) involvement as autoimmune cerebritis is rare but may be devastating. We report a patient having CNS involvement in the form of Parkinsonism long before the development of typical upper and lower airway symptoms. Granulomatosis with polyangiitis was diagnosed on the basis of cavitary lung lesions along with epistaxis, granulomatous inflammation from fine needle aspiration (FNAC) of lymph node and high titer of c-ANCA. The patient was commenced on intravenous methylprednisolone followed by mycophenolate mofetil and responded to treatment. Autoimmune cerebritis may present with subacute manifestation of diffuse CNS involvement. |
| first_indexed | 2024-12-10T22:39:35Z |
| format | Article |
| id | doaj.art-74fe3fd48b78456e8344fa83ff06f737 |
| institution | Directory Open Access Journal |
| issn | 2074-2908 2224-7750 |
| language | English |
| last_indexed | 2024-12-10T22:39:35Z |
| publishDate | 2016-12-01 |
| publisher | Bangabandhu Sheikh Mujib Medical University |
| record_format | Article |
| series | Bangabandhu Sheikh Mujib Medical University Journal |
| spelling | doaj.art-74fe3fd48b78456e8344fa83ff06f7372022-12-22T01:30:45ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502016-12-019410.3329/bsmmuj.v9i4.3033219592Granulomatosis with polyangiitisZubayer Ahmad0Sadiqa Tuqan1Mirza Nazimuddin2Rama Biswas3Anindita Roy4Department of Internal Medicine and Rheumatology, Square Hospital Limited, DhakaDepartment of Internal Medicine and Rheumatology, Square Hospital Limited, DhakaDepartment of Internal Medicine and Rheumatology, Square Hospital Limited, DhakaDepartment of Internal Medicine and Rheumatology, Square Hospital Limited, DhakaDepartment of Internal Medicine and Rheumatology, Square Hospital Limited, DhakaGranulomatosis with polyangiitis is a small and medium vessel vasculitis. It may affect any organ system. Neurological involvement, though less frequent, mostly manifests as peripheral neuropathy. Central nervous system (CNS) involvement as autoimmune cerebritis is rare but may be devastating. We report a patient having CNS involvement in the form of Parkinsonism long before the development of typical upper and lower airway symptoms. Granulomatosis with polyangiitis was diagnosed on the basis of cavitary lung lesions along with epistaxis, granulomatous inflammation from fine needle aspiration (FNAC) of lymph node and high titer of c-ANCA. The patient was commenced on intravenous methylprednisolone followed by mycophenolate mofetil and responded to treatment. Autoimmune cerebritis may present with subacute manifestation of diffuse CNS involvement.https://www.banglajol.info/index.php/BSMMUJ/article/view/30332GranulomatosisPolyangiitis |
| spellingShingle | Zubayer Ahmad Sadiqa Tuqan Mirza Nazimuddin Rama Biswas Anindita Roy Granulomatosis with polyangiitis Bangabandhu Sheikh Mujib Medical University Journal Granulomatosis Polyangiitis |
| title | Granulomatosis with polyangiitis |
| title_full | Granulomatosis with polyangiitis |
| title_fullStr | Granulomatosis with polyangiitis |
| title_full_unstemmed | Granulomatosis with polyangiitis |
| title_short | Granulomatosis with polyangiitis |
| title_sort | granulomatosis with polyangiitis |
| topic | Granulomatosis Polyangiitis |
| url | https://www.banglajol.info/index.php/BSMMUJ/article/view/30332 |
| work_keys_str_mv | AT zubayerahmad granulomatosiswithpolyangiitis AT sadiqatuqan granulomatosiswithpolyangiitis AT mirzanazimuddin granulomatosiswithpolyangiitis AT ramabiswas granulomatosiswithpolyangiitis AT aninditaroy granulomatosiswithpolyangiitis |