Circulating Mature PCSK9 Level Predicts Diminished Response to Statin Therapy

Circulating Mature PCSK9 Level Predicts Diminished Response to Statin Therapy

Background Statin‐mediated efficacy of lowering low‐density lipoprotein (LDL) cholesterol varies in each individual, and its diminished response is associated with worse outcomes. However, there is no established approach to predict hyporesponse to statins. PCSK9 (proprotein convertase subxilisin/ke...

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Bibliographic Details
Main Authors: Naoto Kuyama, Yu Kataoka, Misa Takegami, Kunihiro Nishimura, Mariko Harada‐Shiba, Mika Hori, Masatsune Ogura, Fumiyuki Otsuka, Yasuhide Asaumi, Teruo Noguchi, Kenichi Tsujita, Satoshi Yasuda
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
LDL‐C
proprotein convertase subxilisin/kexin type 9
statin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.019525

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