Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center

Lipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This study aims to provide further insights into the characteristics of lipe...

Full description

Bibliographic Details
Main Authors: Matthias Hamatschek, Henning Knors, Marie-Luise Klietz, Philipp Wiebringhaus, Matthias Aitzetmueller, Tobias Hirsch, Maximilian Kueckelhaus
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/10/2836
_version_ 1797498886012534784
author Matthias Hamatschek
Henning Knors
Marie-Luise Klietz
Philipp Wiebringhaus
Matthias Aitzetmueller
Tobias Hirsch
Maximilian Kueckelhaus
author_facet Matthias Hamatschek
Henning Knors
Marie-Luise Klietz
Philipp Wiebringhaus
Matthias Aitzetmueller
Tobias Hirsch
Maximilian Kueckelhaus
author_sort Matthias Hamatschek
collection DOAJ
description Lipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This study aims to provide further insights into the characteristics of lipedema patients of all stages and provide a baseline prior to surgery for a surgical treatment evaluation by means of patient-reported outcome measures. Methods: Patients completed a lipedema-specific questionnaire containing 50 items, the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Patient Health Questionnaire 9 (PHQ-9). The data were analyzed using SPSS statistics 27. Patients who had already received liposuction were excluded. Results: Five hundred and eleven patients were included, of whom 337 completed the PHQ9 and 333 completed the WHOQOL-BREF questionnaires. The general characteristics of lipedema patients, especially the daily symptoms, are described. Previous observations, such as the frequent occurrence of hypothyroidism and the low rate of type 2 diabetes, were confirmed. Over 49% suffer from severe impairments in their jobs, whereby the disease shows a familial accumulation. The results of the WHOQOL-BREF and the PHQ-9 suggest a high level of mental stress. Discussion: As surgical intervention in lipedema patients is gaining traction, its effects should be well-documented. Therefore, a comprehensive baseline needs to be established prior to surgical treatment. The psychological components are just as important as the inclusion of daily impairments.
first_indexed 2024-03-10T03:39:39Z
format Article
id doaj.art-74ff1b9f836247a4ac346d6b4eda6473
institution Directory Open Access Journal
issn 2077-0383
language English
last_indexed 2024-03-10T03:39:39Z
publishDate 2022-05-01
publisher MDPI AG
record_format Article
series Journal of Clinical Medicine
spelling doaj.art-74ff1b9f836247a4ac346d6b4eda64732023-11-23T11:35:36ZengMDPI AGJournal of Clinical Medicine2077-03832022-05-011110283610.3390/jcm11102836Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume CenterMatthias Hamatschek0Henning Knors1Marie-Luise Klietz2Philipp Wiebringhaus3Matthias Aitzetmueller4Tobias Hirsch5Maximilian Kueckelhaus6Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Fachklinik Hornheide, 48157 Muenster, GermanyLipedema patients suffer not only from visual stigma but also reduction in their quality of life through pain and performance loss in daily life. In clinical practice, it is still difficult to reliably diagnose the disease. This study aims to provide further insights into the characteristics of lipedema patients of all stages and provide a baseline prior to surgery for a surgical treatment evaluation by means of patient-reported outcome measures. Methods: Patients completed a lipedema-specific questionnaire containing 50 items, the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Patient Health Questionnaire 9 (PHQ-9). The data were analyzed using SPSS statistics 27. Patients who had already received liposuction were excluded. Results: Five hundred and eleven patients were included, of whom 337 completed the PHQ9 and 333 completed the WHOQOL-BREF questionnaires. The general characteristics of lipedema patients, especially the daily symptoms, are described. Previous observations, such as the frequent occurrence of hypothyroidism and the low rate of type 2 diabetes, were confirmed. Over 49% suffer from severe impairments in their jobs, whereby the disease shows a familial accumulation. The results of the WHOQOL-BREF and the PHQ-9 suggest a high level of mental stress. Discussion: As surgical intervention in lipedema patients is gaining traction, its effects should be well-documented. Therefore, a comprehensive baseline needs to be established prior to surgical treatment. The psychological components are just as important as the inclusion of daily impairments.https://www.mdpi.com/2077-0383/11/10/2836lipedemaliposuctionQoLdepressionobesityrestrictions in daily life
spellingShingle Matthias Hamatschek
Henning Knors
Marie-Luise Klietz
Philipp Wiebringhaus
Matthias Aitzetmueller
Tobias Hirsch
Maximilian Kueckelhaus
Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
Journal of Clinical Medicine
lipedema
liposuction
QoL
depression
obesity
restrictions in daily life
title Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
title_full Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
title_fullStr Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
title_full_unstemmed Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
title_short Characteristics and Patient Reported Outcome Measures in Lipedema Patients—Establishing a Baseline for Treatment Evaluation in a High-Volume Center
title_sort characteristics and patient reported outcome measures in lipedema patients establishing a baseline for treatment evaluation in a high volume center
topic lipedema
liposuction
QoL
depression
obesity
restrictions in daily life
url https://www.mdpi.com/2077-0383/11/10/2836
work_keys_str_mv AT matthiashamatschek characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT henningknors characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT marieluiseklietz characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT philippwiebringhaus characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT matthiasaitzetmueller characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT tobiashirsch characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter
AT maximiliankueckelhaus characteristicsandpatientreportedoutcomemeasuresinlipedemapatientsestablishingabaselinefortreatmentevaluationinahighvolumecenter