Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period
Abstract Background Since November 2019, the rapid outbreak of coronavirus disease 2019 (COVID-19) has become a public health emergency of international concern. COVID-19 disease is caused by a new variant of coronavirus, named as ‘severe acute respiratory syndrome coronavirus 2.’ Chest CT has a pot...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-07-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
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| Online Access: | https://doi.org/10.1186/s43055-022-00832-x |
| _version_ | 1818162644809416704 |
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| author | Swati Sharma Anjali Aggarwal Rajat K. Sharma Elisheba Patras Annu Singhal |
| author_facet | Swati Sharma Anjali Aggarwal Rajat K. Sharma Elisheba Patras Annu Singhal |
| author_sort | Swati Sharma |
| collection | DOAJ |
| description | Abstract Background Since November 2019, the rapid outbreak of coronavirus disease 2019 (COVID-19) has become a public health emergency of international concern. COVID-19 disease is caused by a new variant of coronavirus, named as ‘severe acute respiratory syndrome coronavirus 2.’ Chest CT has a potential role in the diagnosis, detection of complications and in predicting clinical recovery of patients or progression of coronavirus disease 2019. Degree and severity of lung involvement can be assessed by 25 point CT severity score. This quantification plays an important role to modify the treatment plan at times in critically ill patient of COVID-19. Hence, the purpose of present study was to describe and quantify the severity of COVID-19 infection on chest computed tomography (CT) by 25-point CT severity score and to determine the relationship of CT severity score with clinical and laboratory parameters. Results A total of 150 patients with COVID-19 disease were assessed. Mean age of the study group was 54.46 years (62.7% males and 37.3% females). The most common comorbidity present in the study group was diabetes mellitus, which was present in 17.3% cases. Severity of disease was significantly associated with age of the patient. CT severity score was positively correlated with lymphopenia and raised CRP, D-dimer and serum ferritin levels. A significant statistical correlation was found between CT severity grade and patient survival. Conclusions This is a large comprehensive study, collecting data from 150 cases of COVID-19 pneumonia patients, in a tertiary care hospital in India to describe the correlation of CT severity score with clinical land laboratory parameters. Chest CT severity score correlates well with laboratory parameters and can aid in predicting COVID-19 disease outcome. |
| first_indexed | 2024-12-11T16:36:57Z |
| format | Article |
| id | doaj.art-7500223ae1fb4d9ab471df5c8ed74512 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-11T16:36:57Z |
| publishDate | 2022-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-7500223ae1fb4d9ab471df5c8ed745122022-12-22T00:58:25ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-07-015311810.1186/s43055-022-00832-xCorrelation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic periodSwati Sharma0Anjali Aggarwal1Rajat K. Sharma2Elisheba Patras3Annu Singhal4Department of Radiodiagnosis, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. RML HospitalDepartment of Radiodiagnosis, St. Stephens HospitalDepartment of Radiodiagnosis, St.Stephens Hospital, Tis HazariDepartment of Radiodiagnosis, St.Stephens Hospital, Tis HazariDepartment of Radiodiagnosis, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. RML HospitalAbstract Background Since November 2019, the rapid outbreak of coronavirus disease 2019 (COVID-19) has become a public health emergency of international concern. COVID-19 disease is caused by a new variant of coronavirus, named as ‘severe acute respiratory syndrome coronavirus 2.’ Chest CT has a potential role in the diagnosis, detection of complications and in predicting clinical recovery of patients or progression of coronavirus disease 2019. Degree and severity of lung involvement can be assessed by 25 point CT severity score. This quantification plays an important role to modify the treatment plan at times in critically ill patient of COVID-19. Hence, the purpose of present study was to describe and quantify the severity of COVID-19 infection on chest computed tomography (CT) by 25-point CT severity score and to determine the relationship of CT severity score with clinical and laboratory parameters. Results A total of 150 patients with COVID-19 disease were assessed. Mean age of the study group was 54.46 years (62.7% males and 37.3% females). The most common comorbidity present in the study group was diabetes mellitus, which was present in 17.3% cases. Severity of disease was significantly associated with age of the patient. CT severity score was positively correlated with lymphopenia and raised CRP, D-dimer and serum ferritin levels. A significant statistical correlation was found between CT severity grade and patient survival. Conclusions This is a large comprehensive study, collecting data from 150 cases of COVID-19 pneumonia patients, in a tertiary care hospital in India to describe the correlation of CT severity score with clinical land laboratory parameters. Chest CT severity score correlates well with laboratory parameters and can aid in predicting COVID-19 disease outcome.https://doi.org/10.1186/s43055-022-00832-xCOVID-19CT severity scorePandemicClinical |
| spellingShingle | Swati Sharma Anjali Aggarwal Rajat K. Sharma Elisheba Patras Annu Singhal Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period The Egyptian Journal of Radiology and Nuclear Medicine COVID-19 CT severity score Pandemic Clinical |
| title | Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period |
| title_full | Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period |
| title_fullStr | Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period |
| title_full_unstemmed | Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period |
| title_short | Correlation of chest CT severity score with clinical parameters in COVID-19 pulmonary disease in a tertiary care hospital in Delhi during the pandemic period |
| title_sort | correlation of chest ct severity score with clinical parameters in covid 19 pulmonary disease in a tertiary care hospital in delhi during the pandemic period |
| topic | COVID-19 CT severity score Pandemic Clinical |
| url | https://doi.org/10.1186/s43055-022-00832-x |
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