Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer
With the help of immunohistochemcial methods the frequency of estrogen and progesteron expression in tumor tissue of 30 patients with non-small cell lung cancer was analysed, positive result took place in 1 patient (3%). Assessment of effi ciency of high dose tamoxifenotherapy in combined treatment...
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2012-12-01
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| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/18028/15777 |
| _version_ | 1818277003273437184 |
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| author | A. I. Shevchenko A. V. Kadzhoyan |
| author_facet | A. I. Shevchenko A. V. Kadzhoyan |
| author_sort | A. I. Shevchenko |
| collection | DOAJ |
| description | With the help of immunohistochemcial methods the frequency of estrogen and progesteron expression in tumor tissue of 30 patients with non-small cell lung cancer was analysed, positive result took place in 1 patient (3%). Assessment of effi ciency of high dose tamoxifenotherapy in combined treatment was performed in 45 patients with III-IV stages of non-small cell lung cancer (control group – 39 patients received chemotherapy only); the results obtained were signifi cantly better in achieving of partial regression and stabilization of the disease in the study group. |
| first_indexed | 2024-12-12T22:54:38Z |
| format | Article |
| id | doaj.art-7504d777b3574314bf58a44a1e2e6469 |
| institution | Directory Open Access Journal |
| issn | 2306-4145 2310-1210 |
| language | English |
| last_indexed | 2024-12-12T22:54:38Z |
| publishDate | 2012-12-01 |
| publisher | Zaporozhye State Medical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj.art-7504d777b3574314bf58a44a1e2e64692022-12-22T00:08:58ZengZaporozhye State Medical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102012-12-0164951http://dx.doi.org/10.14739/2310-1210.2012.6.18028Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancerA. I. Shevchenko A. V. KadzhoyanWith the help of immunohistochemcial methods the frequency of estrogen and progesteron expression in tumor tissue of 30 patients with non-small cell lung cancer was analysed, positive result took place in 1 patient (3%). Assessment of effi ciency of high dose tamoxifenotherapy in combined treatment was performed in 45 patients with III-IV stages of non-small cell lung cancer (control group – 39 patients received chemotherapy only); the results obtained were signifi cantly better in achieving of partial regression and stabilization of the disease in the study group.http://zmj.zsmu.edu.ua/article/view/18028/15777non-small cell lung cancertamoxifenreceptorsestrogenprogesteronchemohormonal treatment |
| spellingShingle | A. I. Shevchenko A. V. Kadzhoyan Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer Zaporožskij Medicinskij Žurnal non-small cell lung cancer tamoxifen receptors estrogen progesteron chemohormonal treatment |
| title | Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer |
| title_full | Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer |
| title_fullStr | Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer |
| title_full_unstemmed | Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer |
| title_short | Analysis of high-dose tamoxifen therapy efficiency in complex treatment of patients with stage III-IV non-small cell lung cancer |
| title_sort | analysis of high dose tamoxifen therapy efficiency in complex treatment of patients with stage iii iv non small cell lung cancer |
| topic | non-small cell lung cancer tamoxifen receptors estrogen progesteron chemohormonal treatment |
| url | http://zmj.zsmu.edu.ua/article/view/18028/15777 |
| work_keys_str_mv | AT aishevchenko analysisofhighdosetamoxifentherapyefficiencyincomplextreatmentofpatientswithstageiiiivnonsmallcelllungcancer AT avkadzhoyan analysisofhighdosetamoxifentherapyefficiencyincomplextreatmentofpatientswithstageiiiivnonsmallcelllungcancer |