Body temperature as a predictor of mortality in COVID-19
Abstract It remains uncertain if body temperature (BT) is a useful prognostic indicator in coronavirus disease 2019 (COVID-19). We investigated the relationship between BT and mortality in COVID-19 patients. We used a de-identified database that prospectively collected information from patients scre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-40414-z |
| _version_ | 1797560199825850368 |
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| author | Shuhei Uchiyama Tomoki Sakata Serena Tharakan Kiyotake Ishikawa |
| author_facet | Shuhei Uchiyama Tomoki Sakata Serena Tharakan Kiyotake Ishikawa |
| author_sort | Shuhei Uchiyama |
| collection | DOAJ |
| description | Abstract It remains uncertain if body temperature (BT) is a useful prognostic indicator in coronavirus disease 2019 (COVID-19). We investigated the relationship between BT and mortality in COVID-19 patients. We used a de-identified database that prospectively collected information from patients screened for COVID-19 at the Mount Sinai facilities from February 28, 2020 to July 28, 2021. All patients diagnosed with COVID-19 that had BT data were included. BT at initial presentation, maximum BT during hospitalization, comorbidity, and vaccination status data were extracted. Mortality rate was assessed as a primary outcome. Among 24,293 cases, patients with initial BT below 36 °C had higher mortality than those with BT of 36–37 °C (p < 0.001, odds ratio 2.82). Initial BT > 38 °C was associated with high mortality with an incremental trend at higher BT. In 10,503 in-patient cases, a positive association was observed between mortality and maximum BT except in patients with BT < 36 °C. Multiple logistic regression analyses including the comorbidities revealed that maximum BT was an independent predictor of mortality. While vaccination did not change the distribution of maximum BT, mortality was decreased in vaccinated patients. Our retrospective cohort study suggests that high maximum BT is an independent predictor of higher mortality in COVID-19 patients. |
| first_indexed | 2024-03-10T17:57:02Z |
| format | Article |
| id | doaj.art-75054628476f41c9a88104bef359e1cd |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-10T17:57:02Z |
| publishDate | 2023-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-75054628476f41c9a88104bef359e1cd2023-11-20T09:10:28ZengNature PortfolioScientific Reports2045-23222023-08-011311810.1038/s41598-023-40414-zBody temperature as a predictor of mortality in COVID-19Shuhei Uchiyama0Tomoki Sakata1Serena Tharakan2Kiyotake Ishikawa3Cardiovascular Research Institute, Icahn School of Medicine at Mount SinaiCardiovascular Research Institute, Icahn School of Medicine at Mount SinaiCardiovascular Research Institute, Icahn School of Medicine at Mount SinaiCardiovascular Research Institute, Icahn School of Medicine at Mount SinaiAbstract It remains uncertain if body temperature (BT) is a useful prognostic indicator in coronavirus disease 2019 (COVID-19). We investigated the relationship between BT and mortality in COVID-19 patients. We used a de-identified database that prospectively collected information from patients screened for COVID-19 at the Mount Sinai facilities from February 28, 2020 to July 28, 2021. All patients diagnosed with COVID-19 that had BT data were included. BT at initial presentation, maximum BT during hospitalization, comorbidity, and vaccination status data were extracted. Mortality rate was assessed as a primary outcome. Among 24,293 cases, patients with initial BT below 36 °C had higher mortality than those with BT of 36–37 °C (p < 0.001, odds ratio 2.82). Initial BT > 38 °C was associated with high mortality with an incremental trend at higher BT. In 10,503 in-patient cases, a positive association was observed between mortality and maximum BT except in patients with BT < 36 °C. Multiple logistic regression analyses including the comorbidities revealed that maximum BT was an independent predictor of mortality. While vaccination did not change the distribution of maximum BT, mortality was decreased in vaccinated patients. Our retrospective cohort study suggests that high maximum BT is an independent predictor of higher mortality in COVID-19 patients.https://doi.org/10.1038/s41598-023-40414-z |
| spellingShingle | Shuhei Uchiyama Tomoki Sakata Serena Tharakan Kiyotake Ishikawa Body temperature as a predictor of mortality in COVID-19 Scientific Reports |
| title | Body temperature as a predictor of mortality in COVID-19 |
| title_full | Body temperature as a predictor of mortality in COVID-19 |
| title_fullStr | Body temperature as a predictor of mortality in COVID-19 |
| title_full_unstemmed | Body temperature as a predictor of mortality in COVID-19 |
| title_short | Body temperature as a predictor of mortality in COVID-19 |
| title_sort | body temperature as a predictor of mortality in covid 19 |
| url | https://doi.org/10.1038/s41598-023-40414-z |
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