Pericellular collagen I coating for enhanced homing and chondrogenic differentiation of mesenchymal stem cells in direct intra-articular injection

Pericellular collagen I coating for enhanced homing and chondrogenic differentiation of mesenchymal stem cells in direct intra-articular injection

Abstract Background Direct intra-articular injection (DIAI) of mesenchymal stem cells (MSCs) is a promising technique for cartilage repair. However, the repair process was hindered by the absence of scaffold and poor cell–matrix interactions. Methods In this study, we developed a pericellular collag...

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Bibliographic Details
Main Authors: Hansong Xia, Chi Liang, Pan Luo, Junjie Huang, Jinshen He, Zili Wang, Xu Cao, Cheng Peng, Song Wu
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Stem Cell Research & Therapy
Subjects:
Cartilage injury
Cartilage repair
Chondrogenic differentiation
Bone marrow mesenchymal stem cells
Homing
Online Access:http://link.springer.com/article/10.1186/s13287-018-0916-z

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