The Cancer Genome Atlas Database and Its Application

Cancer is uncontrolled growth of cells that caused by DNA variations. Identifying the variations and their interactions in each cancer's genome will accelerate the understanding of the molecular basis of cancer. This work will improve our abilities of cancer prevention, early detection and trea...

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Main Authors: SUN Jizheng, TANG Yujing, SA Rongbo, GAO Yanxia
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2018-03-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.0814.htm
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author SUN Jizheng
TANG Yujing
SA Rongbo
GAO Yanxia
author_facet SUN Jizheng
TANG Yujing
SA Rongbo
GAO Yanxia
author_sort SUN Jizheng
collection DOAJ
description Cancer is uncontrolled growth of cells that caused by DNA variations. Identifying the variations and their interactions in each cancer's genome will accelerate the understanding of the molecular basis of cancer. This work will improve our abilities of cancer prevention, early detection and treatment. So, American National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI) initiated. The Cancer Genome Atlas (TCGA) project. Unprecedented amount of data was generated in the process. We can learn more about the molecular basis of cancer by analyzing the data from TCGA, to lay the foundation for precision therapy and personalized cancer care. In this paper, we introduced the development of data, data types and levels, retrieval and application, and benefits of TCGA in detail. Our introductions aim to help researchers learn and use the dataset to develop more effective ways to diagnose, treat and prevent cancer.
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spelling doaj.art-7507a0b8d3e249a2ab58787a1d67600a2022-12-21T18:53:46ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782018-03-0145317117410.3971/j.issn.1000-8578.2018.17.08148578.2018.17.0814The Cancer Genome Atlas Database and Its ApplicationSUN Jizheng0TANG Yujing1SA Rongbo2GAO Yanxia3College of Life Science, Taishan Medical University, Taian 271016, ChinaCollege of Life Science, Taishan Medical University, Taian 271016, ChinaCollege of Life Science, Taishan Medical University, Taian 271016, ChinaCollege of Life Science, Taishan Medical University, Taian 271016, ChinaCancer is uncontrolled growth of cells that caused by DNA variations. Identifying the variations and their interactions in each cancer's genome will accelerate the understanding of the molecular basis of cancer. This work will improve our abilities of cancer prevention, early detection and treatment. So, American National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI) initiated. The Cancer Genome Atlas (TCGA) project. Unprecedented amount of data was generated in the process. We can learn more about the molecular basis of cancer by analyzing the data from TCGA, to lay the foundation for precision therapy and personalized cancer care. In this paper, we introduced the development of data, data types and levels, retrieval and application, and benefits of TCGA in detail. Our introductions aim to help researchers learn and use the dataset to develop more effective ways to diagnose, treat and prevent cancer.http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.0814.htmthe cancer genome atlas (tcga) projectdatabasedata typesretrieval and application of data
spellingShingle SUN Jizheng
TANG Yujing
SA Rongbo
GAO Yanxia
The Cancer Genome Atlas Database and Its Application
Zhongliu Fangzhi Yanjiu
the cancer genome atlas (tcga) project
database
data types
retrieval and application of data
title The Cancer Genome Atlas Database and Its Application
title_full The Cancer Genome Atlas Database and Its Application
title_fullStr The Cancer Genome Atlas Database and Its Application
title_full_unstemmed The Cancer Genome Atlas Database and Its Application
title_short The Cancer Genome Atlas Database and Its Application
title_sort cancer genome atlas database and its application
topic the cancer genome atlas (tcga) project
database
data types
retrieval and application of data
url http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.0814.htm
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