Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

Abstract Despite the large public health toll of smoking, genetic studies of smoking cessation have been limited with few discoveries of risk or protective loci. We investigated common and rare variant associations with success in quitting smoking using a cohort from 8 randomized controlled trials i...

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Bibliographic Details
Main Authors: Paul M. Cinciripini, David W. Wetter, Jian Wang, Robert Yu, George Kypriotakis, Tapsi Kumar, Jason D. Robinson, Yong Cui, Charles E. Green, Andrew W. Bergen, Thomas R. Kosten, Steven E. Scherer, Sanjay Shete
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Smoking cessation
Candidate gene study
Single-nucleotide polymorphism
Rare variant
Sequencing
Online Access:https://doi.org/10.1038/s41598-024-56750-7

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