Potential Use of Anti-Inflammatory Synthetic Heparan Sulfate to Attenuate Liver Damage

Potential Use of Anti-Inflammatory Synthetic Heparan Sulfate to Attenuate Liver Damage

Heparan sulfate is a highly sulfated polysaccharide abundant on the surface of hepatocytes and surrounding extracellular matrix. Emerging evidence demonstrates that heparan sulfate plays an important role in neutralizing the activities of proinflammatory damage associate molecular patterns (DAMPs) t...

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Bibliographic Details
Main Authors: Katelyn Arnold, Yi-En Liao, Jian Liu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
heparan sulfate
chemoenzymatic synthesis
oligosaccharides
DAMPS
inflammation
Online Access:https://www.mdpi.com/2227-9059/8/11/503

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