MiR-21 alleviates renal tubular epithelial cells injury induced by ischemia by targeting TLR4

MiR-21 alleviates renal tubular epithelial cells injury induced by ischemia by targeting TLR4

Renal ischemia is the initial stage of kidney damage, leading to mitochondrial metabolism disorders and cell necrosis. In this study, we aimed to investigate the biological functions and potential mechanisms of miR-21 in protecting renal tubular epithelial cells from oxidative stress and apoptosis f...

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Bibliographic Details
Main Authors:	Xiu-Juan Liu, Jin-Lei Lv, Xin Zou, Yan-Yan Yu, Hong-Xia Zhou, Yu Wu, Yan-Qiu Geng, Cai-Hua Lie
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Series:	Heliyon
Subjects:	miR-21 TLR4 AKT Ischemia Renal HIF-1α
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844023030256

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