Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site
We describe the clinicopathological features of a solid variant of orbital angioleiomyoma. A review of clinical records, diagnostic, and radiographic studies combined with histopathological evaluation with standard histochemical staining and immunohistochemistry was conducted. A 22-year-old male pat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2016;volume=64;issue=6;spage=466;epage=468;aulast=Nair |
| _version_ | 1828760420759896064 |
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| author | Akshay Gopinathan Nair Vandana Jain Indumati Gopinathan Anuradha Murthy |
| author_facet | Akshay Gopinathan Nair Vandana Jain Indumati Gopinathan Anuradha Murthy |
| author_sort | Akshay Gopinathan Nair |
| collection | DOAJ |
| description | We describe the clinicopathological features of a solid variant of orbital angioleiomyoma. A review of clinical records, diagnostic, and radiographic studies combined with histopathological evaluation with standard histochemical staining and immunohistochemistry was conducted. A 22-year-old male patient presented with a mass in the region of the left lacrimal gland that was gradually increasing over the past 2 years. Radiological and clinical examinations showed no signs suspicious of a malignancy and fine needle aspiration cytology was inconclusive. Therefore, an excision biopsy was performed. On histopathological examination, the picture was consistent with a benign spindle cell tumor. Immunohistochemistry showed positivity for CD 34 and CD 31 (markers for vascular endothelium). The tumor also showed positivity for smooth muscle actin and Ki-67 proliferative index was low. Angioleiomyomas are rarely encountered in the orbit and has features seen in leiomyoma as well as some vascular tumor elements. In most cases, surgical excision is usually curative. |
| first_indexed | 2024-12-11T01:13:46Z |
| format | Article |
| id | doaj.art-75169a2c78304a3a9d49d86796cb662f |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-11T01:13:46Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-75169a2c78304a3a9d49d86796cb662f2022-12-22T01:25:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892016-01-0164646646810.4103/0301-4738.187680Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual siteAkshay Gopinathan NairVandana JainIndumati GopinathanAnuradha MurthyWe describe the clinicopathological features of a solid variant of orbital angioleiomyoma. A review of clinical records, diagnostic, and radiographic studies combined with histopathological evaluation with standard histochemical staining and immunohistochemistry was conducted. A 22-year-old male patient presented with a mass in the region of the left lacrimal gland that was gradually increasing over the past 2 years. Radiological and clinical examinations showed no signs suspicious of a malignancy and fine needle aspiration cytology was inconclusive. Therefore, an excision biopsy was performed. On histopathological examination, the picture was consistent with a benign spindle cell tumor. Immunohistochemistry showed positivity for CD 34 and CD 31 (markers for vascular endothelium). The tumor also showed positivity for smooth muscle actin and Ki-67 proliferative index was low. Angioleiomyomas are rarely encountered in the orbit and has features seen in leiomyoma as well as some vascular tumor elements. In most cases, surgical excision is usually curative.http://www.ijo.in/article.asp?issn=0301-4738;year=2016;volume=64;issue=6;spage=466;epage=468;aulast=NairAngioleiomyomahemangiomalacrimal glandorbitproptosistumor |
| spellingShingle | Akshay Gopinathan Nair Vandana Jain Indumati Gopinathan Anuradha Murthy Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site Indian Journal of Ophthalmology Angioleiomyoma hemangioma lacrimal gland orbit proptosis tumor |
| title | Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site |
| title_full | Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site |
| title_fullStr | Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site |
| title_full_unstemmed | Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site |
| title_short | Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site |
| title_sort | solid variant of orbital angioleiomyoma an unusual tumor at an unusual site |
| topic | Angioleiomyoma hemangioma lacrimal gland orbit proptosis tumor |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2016;volume=64;issue=6;spage=466;epage=468;aulast=Nair |
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