Exploring Scrotal Leiomyomas, Unraveling the Mysteries of a Rare Tumor: A Case Report
Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th century, are characterized by benign pathology from the subcutaneous dartos muscle. We present two cases of middl...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Asian Medical Press Ltd.(H.K.)
2024-01-01
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| Series: | Annals of Urologic Oncology |
| Subjects: | |
| Online Access: | http://auo.asmepress.com/articles/new-56-663.html |
| Summary: | Leiomyomas, originating from smooth muscle cells, are common in the uterus but rare in
the scrotum, presenting a clinical challenge. Scrotal leiomyomas, first described in the 19th
century, are characterized by benign pathology from the subcutaneous dartos muscle.
We present two cases of middle-aged males with scrotal leiomyomas, detailing clinical
presentations, histopathological findings, and immunohistochemistry results. The first involved
a 48-year-old with a painless scrotal lump, excised to reveal well-circumscribed smooth
muscle bundles. Immunohistochemistry confirmed vimentin, desmin, and smooth muscle
actin (SMA) positivity, consistent with scrotal leiomyoma. The second case featured a 25-yearold with a painless scrotal swelling, histologically matching the features of scrotal leiomyoma.
Accurate diagnosis is crucial for guiding appropriate management strategies. Clinicians
often employ a combination of clinical evaluation, imaging studies, and histopathological
examination to confirm the presence of scrotal leiomyomas. Ultrasound remains a valuable
tool for assessing the size, location, and vascularity of the tumor, aiding in the formulation of a
differential diagnosis. Definitive diagnosis, however, relies on histological examination, which
typically reveals spindle-shaped smooth muscle cells arranged in interlacing bundles. |
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| ISSN: | 2617-7765 2617-7773 |